Electrocoagulation (EC) is an alternative and green technique for wastewater treatment due to of its high removal efficiency, lack of chemical requirements, use of simple devices, lack of secondary pollution, etc. The aim of the present work is to investigates optimum conditions for achieving simultaneous removal of chromium and cadmium ions from synthetic industrial wastewater by EC. The present work investigated the performance of EC in removal of chromium and cadmium via studying the effect of existence of anions (SO42- and Cl-), the existence of other cations (Ni2+ – Zn2+ – Cu2+), electrode surface area and shape and reactor cross section. In addition, the use of two plates as anode or cathode has been investigated. Results showed that the larger the surface area of anode the better removal efficiency of Cr and Cd ions, however increasing the cathode area caused slight increase in the removal process. Having sulfate anion, the removal percent reached nearly 95% and 91% for Cr and Cd ions respectively within half an hour. The existence of Ni reduced the Cr removal efficiency decreased from 98% to 85% in existence of Ni ions , and from 98% to 75.30% in existence of Zn ions and from 98% to 70 % in existence Cu ions and 70%. Moreover, these cations minimized the Cd ion removal percent to the third. The best removal efficiency achieved was about 97 % and 88 % for Cr and Cd ions respectively. The used configuration was Fe/Al electrodes, 1.0A average applied current and solution with sulfate anions only after one hour, consequently. The study showed that use of EC is recommended for the removal of such heavy metals ions from industrial wastewater as chromium and cadmium.