Background and Objectives: The relationship between mitral L-wave and other mitral inflow parameters and its characteristics has not been previously addressed in patients with different ejection fraction (EF) phenotypes without heart failure. Methods: We studied 112 patients with prominent L-Wave, for the E, A, e`, a`, L, & L` velocities; R-E, R-e`, E-L & e`-L`, IVR, E & L deceleration times (EDT&LDT); E/A, E/L, & E/e` ratios of the mitral inflow, LV EF%& LAVI. Results: Group 1(81%) had a preserved EF(≥50%). Group 2 had a greater LAVI (40±17.4 ml/m2), longer LDT (230±101 msec) and R-E(450±65 msec), p<0.05. L- Wave velocity had positive correlation with E- wave velocity and negative correlations with E-L and E-Lc in all groups. For reduced EF, LDT was positively correlated with LAVI(r=0.6, p=0.04). In preserved EF, L- wave velocity was negatively correlated with LDT(r=-0.4, p=0.01), R-R(r=-0.3, p=0.007) &R-E (r=-5, p<0.001); the LDT had positive correlations with the E-L(r=0.4, p=0.005). Conclusion: Mitral L- wave could be a relevant parameter for evaluating LV diastolic function and filling pressure, especially when associated with a shorter E-L time. The trend in LDT differs between types of EF; it is longer with larger LAVI in reduced EF, but tends to be shorter with preserved EF because the mechanism of maintenance differs. A pathological L- wave appeared at a faster HR.