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Implication of endoplasmic reticulum stress and mitochondrial perturbations in remote liver injury after renal ischemia/reperfusion in rats: potential protective role of azilsartan
Faculty
Pharmacy
Year:
2024
Type of Publication:
ZU Hosted
Pages:
Authors:
Rania Ali Mohamed Ali Elrashedy
Staff Zu Site
Abstract In Staff Site
Journal:
Redox Report Taylor & Francis
Volume:
Keywords :
Implication , endoplasmic reticulum stress , mitochondrial perturbations
Abstract:
The study uncovered the involvement of mitochondrial perturbations, ER stress and apoptosis in liver injury following renal I/R, and suggested AZL as a preconditioning strategy to ameliorate remote liver injury in patients susceptible to renal I/R after adequate clinical testing.
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Rania Ali Mohamed Ali Elrashedy, "Pioglitazone attenuates cardiac fibrosis and hypertrophy in a rat model of diabetic nephropathy", SAGE, 2012
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Rania Ali Mohamed Ali Elrashedy, "Beneficial effects of pioglitazone against cardiovascular injury are enhanced by combination with aliskiren in a rat model of diabetic nephropathy", Willy, 2012
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Rania Ali Mohamed Ali Elrashedy, "Bladder function in mice with inducible smooth muscle-specific deletion of the manganese superoxide dismutase gene", APS, 2015
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Rania Ali Mohamed Ali Elrashedy, "Functional and morphological alterations of the urinary bladder in type 2 diabetic FVBdb/db mice", Elsevier Inc, 2016
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Department Related Publications
Shimaa Mostafa Mostafa Elshazly, "PPAR gamma agonist, pioglitazone, rescues liver damage induced by renal ischemia/reperfusion injury", Elsevier, 2019
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Mona Fouad Mahmoud Abdelaziz, "Albizia harveyi: phytochemical profiling, antioxidant, antidiabetic and hepatoprotective activities of the bark extract", Springer, 2017
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Amro Abdelraof Abdelghany Mahmoud, "Spirulina platensis Lacks Antitumor Effect against Solid Ehrlich Carcinoma in Female Mice", Hindawi, 2015
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Nasreen Mohammed Ibrahim Moussa, "10-Dehydrogingerdione Attenuates Tramadol-Induced Nephrotoxicity by Modulating Renal Oxidative Stress, Inflammation and Apoptosis in Experimental Rats: Role of HO-1 Activation and TLR4/NF-κB/ERK Inhibition", MDPI, 2022
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Samar Abdelmigeed Mohamed Rezk, "Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation", Taylor and francis, 2023
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