Missing pixel imputation presents a critical challenge in image processing and computer vision, particularly in applications such as image restoration and inpainting. The primary objective of this paper is to accurately estimate and reconstruct missing pixel values to restore complete visual information. This paper introduces a novel model called the Enhanced Connected Pixel Identity GAN with Neutrosophic (ECP-IGANN), which is designed to address two fundamental issues inherent in existing GAN architectures for missing pixel generation: (1) mode collapse, which leads to a lack of diversity in generated pixels, and (2) the preservation of pixel integrity within the reconstructed images. ECP-IGANN incorporates two key innovations to improve missing pixel imputation. First, an identity block is integrated into the generation process to facilitate the retention of existing pixel values and ensure consistency. Second, the model calculates the values of the 8-connected neighbouring pixels around each missing pixel, thereby enhancing the coherence and integrity of the imputed pixels. The efficacy of ECP-IGANN was rigorously evaluated through extensive experimentation across five diverse datasets: BigGAN-ImageNet, the 2024 Medical Imaging Challenge Dataset, the Autonomous Vehicles Dataset, the 2024 Satellite Imagery Dataset, and the Fashion and Apparel Dataset 2024. These experiments assessed the model’s performance in terms of diversity, pixel imputation accuracy, and mode collapse mitigation, with results demonstrating significant improvements in the Inception Score (IS) and Fréchet Inception Distance (FID). ECP-IGANN markedly enhanced image segmentation performance in the validation phase across all datasets. Key metrics, such as Dice Score, Accuracy, Precision, and Recall, were improved substantially for various segmentation models, including Spatial Attention U-Net, Dense U-Net, and Residual Attention U-Net. For example, in the 2024 Medical Imaging Challenge Dataset, the Residual Attention U-Net’s Dice Score increased from 0.84 to 0.90, while accuracy improved from 0.88 to 0.93 following the application of ECP-IGANN. Similar performance enhancements were observed with the other datasets, highlighting the model’s robust generalizability across diverse imaging domains.