OBJECTIVE: The aim of the study was to investigate the effect of a 3-month, tram￾poline-based stretch-shortening cycle (SSC) ex￾ercises on muscle strength and postural control in children with Down’s syndrome (DS). PATIENTS AND METHODS: Thirty-two chil￾dren with DS aged between 7-9 years were en￾rolled and randomly assigned into the control group (n = 16); received standard physical ther￾apy (sPT) or SSC group (n = 16); received sPT in addition to a 15-minute, trampoline-based SSC training program twice per week for 12 succes￾sive weeks. Lower limb muscle strength and postural stability [anterior/posterior stability in￾dex (A/P-SI), medial/lateral stability index (M/L￾SI)], and overall stability index (O-SI) were as￾sessed pre- and post-treatment. RESULTS: Strength of hip extensor (p=0.034) and adductor (p=0.015), knee extensor (p=0.028) and flexor (p=0.01), and ankle dorsi (p=0.033) and plantar flexor (p=0.007) muscles increased significantly in the SSC group when com￾pared with the control group. Also, the A/P-SI (p=0.019), M/L-SI (p=0.002), and O-SI (p=0.021) decreased significantly in the SSC group when compared with the control group, suggesting better postural control. CONCLUSIONS: Twelve weeks of trampo￾line-based SSC exercises are likely effective for enhancing muscle strength and postural con￾trol in children with DS and should consequent￾ly be included in the rehabilitation programs for these children.