Background: Workplace stress is a well-documented problem in a number of professions. However, recent studies have shown that women are more likely to be affected by stress than men. Excessive pressure or performance expectations at work are believed to lead to stress. Emotional, physical, and mental symptoms and indicators are all part of this reaction. Office stress develops when demands on employees are greater than their ability to cope with them. Because women being female, their career objectives can be influenced. It can be difficult for women to advance their careers and careers as doctors in various faculties because they lack the inner motivation to overcome the many challenges that stand in their way, identification of protective factors for resiliency and overcoming the barriers for women to achieve their academic success beside their family and life responsibilities. Objectives: To assess work related stress parameters among a group of female postgraduate staff workers, train them to mitigate stress by workplace mental health promotion program and test its feedback. Subjects and Methods: A-Assessment of stress among study group at a baseline using Workplace Stress Model, which measure 5 parameters. B- Measurement of stress hormone (cortisol) in the study group. C- Training and application of workplace health promotion program for 3 months before reassessment of work stress and compare its results. Results: Improvement of work stress parameters and cortisol level was detected after application of the WorkProMentH's Program among participants. Conclusion: Working staff women are vulnerable to work stress. Adaptation on special exercises and coping skills can relieve stress and prevent its drawbacks.