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Epstein-Barr Virus Promotes Tumorigenicity and Worsens Hodgkin Lymphoma Prognosis by Activating JAK/STAT and NF-κB Signaling Pathways
Faculty
Medicine
Year:
2024
Type of Publication:
ZU Hosted
Pages:
Authors:
Rawda Ahmed AbdelHakim AbdulAziz
Staff Zu Site
Abstract In Staff Site
Journal:
IJMS IJMS
Volume:
Keywords :
Epstein-Barr Virus Promotes Tumorigenicity and Worsens
Abstract:
This prospective study recruited 64 CHL patients from 2017 to 2022 at the Faculty of Medicine, Zagazig University Hospital. A biopsy sample was used to detect Epstein Barr nuclear antigen 1 (EBNA-1) and PD-L1, COX-2, and Bcl-xL immunohistochemistry. Patients were followed up every three months during the first two years and then every six months in the following three years. Clinical follow-up included physical examination, CT scan, and PET-CT scan.
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