Clinical, Laboratory and Radiological Predictors of Unfavorable Hospital Admission Course for Diabetic Patients with COVID-19

Faculty Medicine Year: 2021
Type of Publication: ZU Hosted Pages: 9
Authors:
Journal: Egyptian Journal of Hospital Medicine Ain Shams University Faculty of Medicine Volume:
Keywords : Clinical, Laboratory , Radiological Predictors , Unfavorable Hospital    
Abstract:
Hospital Admission Course for Diabetic Patients with COVID-19 Mohamed Sorour Mohamed*1, Tamer M. Gouda1, Ali M. Hassanin2, Nahla Ibrahim Zidan3, Walaa Sabry Fouad4, Amr Shaaban Hanafy1, Hussein Mohammed Hussein 1 Departments of 1Internal Medicine, 2Radiodiagnosis, 3Clinical Pathology and 4Family Medicine, Faculty of Medicine, Zagazig University Hospital, Egypt. Background: Patients with diabetes mellitus infected with the new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are at risk of high morbidity and mortality. Objective: Our study aimed to address the clinical, laboratory and radiological predictors of hospital admission course for patients with diabetes mellitus with COVID19 infection at the time of admission. Patients and Methods: This was a single center, retrospective study of patients with diabetes mellitus (DM) admitted with COVID-19 infection. Patients with unfavorable admission course were compared with those of favorable course regarding patient characteristics, clinical presentation, results of laboratory investigations and chest CT severity score. Univariate and multivariate analysis associated with the unfavorable course was performed. Results: Among 141 patients with DM admitted with COVID19, 44 patients had unfavorable course. Those with the favorable course were significantly younger (53.3±16.4) vs (67.3 ±15.8) in the unfavorable course group, multivariate analysis revealed that age more than 65, presence of hypertension, CT severity scoring, high HBA1c, AST, IL6, oxygen saturation less than 93% and low lymphocyte count were the independent predictors of the unfavorable hospital admission course. Conclusions: Our finding suggests that old age, presence of hypertension, hypoxia at presentation, in addition to high HBA1c, AST, IL6, CT severity scoring and low lymphocyte count were significant predictors of unfavorable admission course in COVID19 patients with diabetes. Keywords: Coronavirus, COVID19, Diabetes mellitus, Predictors, Prognosis.
   
     
 
       

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