Magnetic resonance imaging features of post-COVID-19 regional and invasive sino-nasal mucormycosis

Faculty Medicine Year: 2022
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Egyptian Journal of Radiology and Nuclear Medicine Egyptian Journal of Radiology and Nuclear Medicine Volume:
Keywords : Magnetic resonance imaging features , post-COVID-19 regional    
Abstract:
Background: Sino‑nasal mucormycosis is an opportunistic, invasive fungal disease which has shown a rising trend in the setting of COVID‑19. The objective of this study is to document and analyze demographic data, clinical presenta tion and MR imaging spectra for early detection and management of post‑COVID‑19 sino‑nasal mucormycosis. Results: Sixty‑two cases of sino‑nasal mucormycosis were enrolled in this study; their mean age was 50.65 ± 8.25 years, with significant female predominance. Nine patients (14.5%) had active COVID‑19 and 53 (85.5%) were recent COVID‑19 cases. Sixty patients have not received COVID‑19 vaccine. The mean duration from the initial COVID‑19 laboratory confirmation to the detection of sino‑nasal mucormycosis was 25.7 +/− 4.6 days. Thirty‑five patients (56.5%) were kept in the hospital for COVID management and 4 of them received intensive care unit (ICU) treatment. Twenty‑seven patients (43.5%) were treated in home isolation. Corticosteroids were administered in 48 cases (77.4%). Twenty‑nine patients (46.8%) had been given oxygen for an average time of 11.2 ± 4.15 days. Diabetes was found in 56 cases (90.3%). The most common clinical symptoms were headache, seen in 52 patients (83.87%). The ethmoid sinus was the most common paranasal sinus involved in our study, seen in 47 cases (75.81%). In 36 cases (58%), multiple sinuses were involved. MRI staging according to the extent of regional involvement. Stage 1 seen in 2 cases (3.23%), stage 2 in 13 cases (20.97%), stage 3 in 35 cases (56.45%) and stage 4 in 12 cases (19.35%). Conclusions: MRI shows a spectrum of findings in sino‑nasal mucormycosis. Imaging plays a major role in staging and assessing the extent of involvement and complications. In light of this, mortality and morbidity can be dramati cally decreased with adequate evaluation and therapy
   
     
 
       

Author Related Publications

  • Ahmed Ibrahim Ibrahim Elagroudy, "Interleukin 28 B Gene Polymorphisms as a Predictor of Treatment Response in Egyptians with Chronic Hepatitis C", Zagazig University Medical Journal, 2014 More
  • Ahmed Ibrahim Ibrahim Elagroudy, "Effect of direct acting antiviral on elastographic measures in patients with chronic HCV infection", Egypt J Intern Med, 2019 More
  • Ahmed Ibrahim Ibrahim Elagroudy, "Thyroid Dysfunction in Acute Coronary Syndrome and its Relation to Morbidity and Mortality", International Journal of Science and Research (IJSR), 2015 More
  • Ahmed Ibrahim Ibrahim Elagroudy, "Fecal Calprotectin assessment in cirrhotic patients with hepatic encephalopathy", Egypt J Intern Med, 2019 More
  • Ahmed Ibrahim Ibrahim Elagroudy, "1 Value of Serum Growth Differentiation Factor 15 in diagnosis of Colorectal Cancer", The Egyptian Journal of Hospital Medicine, 2021 More

Department Related Publications

  • Khaled Abdelnaby Khodary Mohamed Elhefnawy, "URINARY INTERLEUKIN-18 AS A BIOMARKER FOR EARLY DIAGNOSIS OF ACUTE KIDNEY INJURY IN INTENSIVE CARE UNIT IN ZAGAZIG UNIVERSITY HOSPITALS", International Journal of Advanced Research (2014), Volume 2, Issue 10, 469-480, 2014 More
  • jehan saeed abdo soliman, "Promoter methylation and expression of intercellular adhesion molecule 1 gene in blood of autoimmune thyroiditis patients", Molecular Biology Reports, 2019 More
  • Ayman Fathy Abdelhaliem Abdelhaliem, "expression of chemokine receptors (cxcr4 and ccr7) in b-chronic lymphatic leukemia,correlation with rai staging.", lpgd, 2010 More
  • Mohammed Rushdie Moetemed, "RELATIONSHIP BETWWEN THYROID FUNCTION AND INTENSIVE CARE UNIT MORTALITY AT ZAGAZIG UNIVERSITY HOSPITALS", ZAGAZIG JOURNAL, 2015 More
  • Majid Mahrous Sharif Sharif, "Microalbuminuria Screening and Risk Factors in Adolescents with Type 1 Diabetes Mellitus In Zagazig University Hospital", British Journal of Science, 2013 More
Tweet