Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
The validity and reproducibility of the thyroid imaging reporting and data system (TI-RADS) in categorization of thyroid nodules: Multicentre prospective study
Faculty
Medicine
Year:
2019
Type of Publication:
ZU Hosted
Pages:
Authors:
Mona Mohamed Refaat esmail
Staff Zu Site
Abstract In Staff Site
Journal:
European journal of radiology Elsevier B.V.
Volume:
Keywords :
, validity , reproducibility , , thyroid imaging reporting , data system
Abstract:
The validity and reproducibility of the thyroid imaging reporting and data system (TI-RADS) in categorization of thyroid nodules: Multicentre prospective study Purpose: To assess diagnostic validity and reproducibility of Thyroid Imaging Reporting and Data System (TI-RADS) for interpretation of thyroid nodules by thyroid ultrasonography (US). Method: A prospective multicentre study initially included 557 patients with clinically suspected thyroid nodules. After exclusion, a final cohort of 380 patients with 948 thyroid nodules detected by US were enrolled. Based on American College of Radiology (ACR) TI-RADS, three radiologists analysed all US examinations independently and assigned a TI-RADS category to each thyroid nodule. The final diagnosis was based on cytology which was used as reference standard for calculating diagnostic performance of TI-RADS for predicting malignant thyroid nodules. The Fleiss and weighted kappa (κ) statistics were applied to assess inter-observer agreement of morphological features and TI-RADS scoring results for thyroid nodules. Additionally, we made a simple screening among referring clinicians to assess the clinical response to application of TI-RADS. Results: A total of 948 thyroid nodules were evaluated; 136 (14.3%) were malignant, and 812 (85.7%) were benign. The papillary carcinoma was the most common malignant thyroid nodules (81.6%). The best cut-off value for predicting malignant thyroid nodules was > TR3. On a lesion-based analysis, the TI-RADS had a sensitivity, specificity, and an accuracy of 98.3%, 90.9%, and 92.1%, respectively when regarding those thyroid nodules classified as > TR3 for predicting malignancy. The inter-observer agreement of the TI-RADS category was good (κ = 0.636). Ninety percent of referring clinicians accept TI-RADS. Conclusions: TI-RADS improves diagnostic performance of US for predicting malignant thyroid nodules with high validity and high reproducibility.
Author Related Publications
Mona Mohamed Refaat esmail, "Role Of Magnetic Resonance Imaging In Evaluation Of Anatomical Causes Of Female Infertility in Zagazig university hospitals", مجلة كلية الطب جامعة الزقازيق, 2017
More
Mona Mohamed Refaat esmail, "The validity and reproducibility of the thyroid imaging reporting and data system (TI-RADS) in categorization of thyroid nodules: Multicentre prospective study", ELSEVIER, 2019
More
Mona Mohamed Refaat esmail, "In Screening Breast Program: Can Automated Breast Ultrasound (ABUS) Have a Role in The Future?", Zagazig University, Zagazig, Egypt, 2022
More
Mona Mohamed Refaat esmail, "Sonographic signs of pediatric ovarian torsion: Multicenter study with surgical correlation", ELSEVIER, 2025
More
Department Related Publications
moenis Muhammad arafa arafa, "Variability in sphenoid sinus pneumatization and its impact upon reduction of complications following sellar region surgeries", The Egyptian Journal of Radiology and Nuclear Medicine (2014) 45, 705–714, 2014
More
Haitham Abdullah Mohammed Mohammed Dawood, "CARDAIC CT CORONARY ANGIOGRAPHY SCREENING OF CORONARY ARTERY DISEASE IN DIABETIC PATIENTS PRESENTED WITH LOW TO INTERMEDIATE RISK CHEST PAIN", المجلة الطبيـة لجامعـة القاهرة, 2013
More
Haitham Abdullah Mohammed Mohammed Dawood, "INTERNAL DERANGEMENT OF THE TEMPOROMANDIBULAR JOINT: VALUE OF MRI IMAGING IN SYMPTOMATIC PATIENTS", المجلة الطبيـة لجامعـة القاهرة, 2014
More
Alsayed Hamed Zedan, "MDCT as the modality of choice in diagnosis of postoperative complications after laparoscopic sleeve gastrectomy", The Egyptian Journal of Radiology andNuclear Medicine, 2016
More
Ahmad AbdelAzim esmaiyl, "CORONARY ARTERY ANOMALIES: ROLE OF CONTRAST ENHANCED MDCT CORONARY ANGIOGRAPHY دور الأشعة المقطعية متعددة الشرائح في تشخيص العيوب الخلقية للشريان التاجي", الجمعية المصرية للأشعة والطب النووي, 2012
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف