Abstract Keywords: Volvulus; Intestinal Malrotation; Neonates; Ladd’s Procedure; Laparoscopy Intestinal malrotation is the name for a variety of intestinal attachments and rotation abnormalities that ranged from a mobile cecum to a complete non-rotation of the intestine with or without an associated volvulus of the midgut and reversed rotation. Patients present with midgut volvulus as a complication of intestinal malrotation during the 1st year of life, mostly within the first seven days [1]. Newborns with intestinal malrotation mostly present with a scaphoid abdomen and bilious vomiting which is associated with midgut volvulus, which leads to serious outcomes in case of a delay in diagnosis and treatment [2]. Ladd in 1938 described a surgical approach for management and is still the main line of management of malrotation [3]. Ladd’s procedure could be performed either by Introduction Background: Ladd’s procedure is the preferred method of management of Intestinal malrotation and could be performed either by laparotomy or by laparoscopy. A number of studies have described successful management of malrotation using laparoscopic approach. But there are few reports about the safety and feasibility of malrotation management using laparoscopy during the neonatal period. In the present study we aimed to compare the clinical outcomes of a group of neonates with intestinal malrotation and volvulus who underwent laparoscopic assisted surgical management with a similar group of patients subjected to the classic open Ladd’s approach. Materials and Methods: The current study included thirty neonates who were suspected to have intestinal malrotation and volvulus and underwent surgery in the period from May 2016 to July 2019. We divided our patients into two groups each group included fifteen neonates the first group underwent laparoscopic assisted surgery and the second group underwent classical open Ladd’s approach. We evaluated the patients to detect the clinical outcome. Results: There were no statistically significant differences between both groups regarding; age or sex of the patients, weight at surgery, comorbidity or primary presentation. The operative time for the first group was longer than operative time for the second group (P = 0.021). The duration of hospital stay and duration of starting full oral diet for the first group was shorter than that for the second group (P <0.001). Conclusion: laparoscopy is a safe, effective and feasible approach for surgical management of intestinal malrotation with volvulus in newborns and children when compared to classical open Ladd’s procedure. laparotomy or by laparoscopy and it cons