Secukinumab and Black Garlic Downregulate OPG/RANK/RANKL Axis and Devitalize Myocardial Interstitial Fibrosis Induced by Sunitinib in Experimental Rats

Faculty Pharmacy Year: 2023
Type of Publication: ZU Hosted Pages:
Authors:
Yasmin Kasem Mahmoud
Journal: Life MDPI Volume:
Keywords : Secukinumab , Black Garlic Downregulate OPG/RANK/RANKL Axis , Devitalize    
Abstract:
Sunitinib has been associated with several cardiotoxic effects such as cardiac fibrosis. The present study was designed to explore the role of interleukin (IL)-17 in sunitinib-induced myocardial fibrosis (MF) in rats and whether its neutral
    
     
 
       

Author Related Publications

  • Yasmin Kasem Mahmoud, "RIVAROXABAN IMPROVES MYOCARDIAL ISCHEMIA REPERFUSION INJURY COMPLICATIONS IN OBESE RATS", International Journal Of Pharmaceutical Sciences And Research, 2015 More
  • Yasmin Kasem Mahmoud, "Empaglifozin ameliorates liver fbrosis in NASH rat model via targeting hepatic NF‑κB/SOX9/OPN signaling and osteocalcin level", Springer nature, 2023 More
  • Yasmin Kasem Mahmoud, "Policosanol ameliorates renal inflammation and pyroptosis in hypercholesterolemic rabbits via modulation of HMGB1/PI3K/mTOR/NLRP3/Caspase-1 pathway", Elsevier Ltd., 2022 More
  • Yasmin Kasem Mahmoud, "10-Dehydrogingerdione Attenuates Tramadol-Induced Nephrotoxicity by Modulating Renal Oxidative Stress, Inflammation and Apoptosis in Experimental Rats: Role of HO-1 Activation and TLR4/NF-κB/ERK Inhibition", MDPI, 2022 More
  • Yasmin Kasem Mahmoud, "Sacubitril/valsartan alleviates sunitinib-induced cardiac fibrosis and oxidative stress via improving TXNIP/TRX system and downregulation of NF-ĸB/Wnt/β-catenin/SOX9 signaling", Elsevier, 2024 More

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  • Mohammed Ibrahim Amin Ibrahim Musa, "Glycemic Variability as a Predictor of Major Adverse Cardiac Events after Percutaneous Coronary Intervention", Journal of Indian College of Cardiology, 2019 More
  • Mohammed Ibrahim Amin Ibrahim Musa, "Impact of Pulse Pressure Reserve on Prediabetics with Typical Chest Pain and Normal Coronary Angiography", Journal of Cardiology & Current Research, 2016 More
  • Mohamed Maher Ahmed Allam, "The Impact of Percutaneous Coronary Intervention of Right Coronary Artery on Right Ventricular Function after Acute Inferior Myocardial Infarction", Zagazig University medical journal, 2024 More
  • Ekhlas Mohamed Elsaied, "Regional Left Ventricular Function Analysis By 128-Row Multi-Detector Computed Tomography in Patients with Coronary Artery Disease", CODEN(USA) : IJPRPM, 2019 More
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