Design and synthesis of novel uracil-linked Schiff bases as dual histone deacetylase type II/topoisomerase type I inhibitors with apoptotic potential

Faculty Pharmacy Year: 2023
Type of Publication: ZU Hosted Pages:
Authors:
Ahmed Gamal Mohamed Abdallah Eissa
Journal: Future Medicinal Chemistry Future Science Volume:
Keywords : Design , synthesis , novel uracil-linked Schiff bases    
Abstract:
Design and synthesis of novel uracil-linked Schiff bases as dual histone deacetylase type II/topoisomerase type I inhibitors with apoptotic potential
    
     
 
       

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  • Ahmed Gamal Mohamed Abdallah Eissa, "Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", taylor and francis online, 2016 More
  • Ahmed Gamal Mohamed Abdallah Eissa, "Design and synthesis of novel uracil-linked Schiff bases as dual histone deacetylase type II/topoisomerase type I inhibitors with apoptotic potential", Future Science, 2023 More
  • Ahmed Gamal Mohamed Abdallah Eissa, "Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation", MDPI, 2023 More
  • Ahmed Gamal Mohamed Abdallah Eissa, "Characterization of the Anti-Biofilm and Anti-Quorum Sensing Activities of the β-Adrenoreceptor Antagonist Atenolol against Gram-Negative Bacterial Pathogens", MDPI, 2022 More
  • Ahmed Gamal Mohamed Abdallah Eissa, "Silencing of Salmonella typhimurium Pathogenesis: Atenolol Acquires Efficient Anti-Virulence Activities", MDPI, 2022 More

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  • Mansour Alsayed Mansour Abokol, "SYNTHESIS OF SOME PYRIMIDO(4,,5,: 4,5) PYRIMIDO(1,6- A) INDOLE OF POTENTIAL ANTIINFLAMMATORY ANTIPYRETIC ACTIVITIES", Zag. J. Pharm. Sci.,Vol 4,No. 1, pp 36 - 42(, 1993 More
  • Mansour Alsayed Mansour Abokol, "REDUCTION OF 2, 3-DICHLOROMALEIC ANHYDRIDE III; ACYLATIVE REDUCTIVE ELIMINATION", Boll. Chim. Farmaceutico – Anno 136 –pp.685-690 n11 Dicembre (, 1997 More
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  • Alsayed Mohamed Mansour Lashen , "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", www.elsevier.com/locate/bmcl, 2016 More
  • Noha Ibrahiem Elsayed Mohamed Zidain, "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", www.elsevier.com/locate/bmcl, 2016 More
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