Green micellar liquid chromatographic analysis of alfuzosin hydrochloride and sildenafil citrate in a binary mixture compared to classical RPLC with stability indicating studies

Faculty Pharmacy Year: 2022
Type of Publication: ZU Hosted Pages:
Authors:
Youstina Mekhail Metias Ibrahim
Journal: Drug Development and Industrial Pharmacy Taylor & Francis Volume:
Keywords : Green micellar liquid chromatographic analysis , alfuzosin    
Abstract:
تعيين مخلوط مادتى ألفوزوسين هيدروكلوريد و سيلدينافيل سترات باستخدام كروماتوجرافيا السائل ذات الكفاءة العالية و استخدام أطوار متحركة تقليدية و اخرى صديقه للبيئة كالمحاليل الغروية (الكيمياء الخضراء) مع الاظهار الطيفى عند طول موجى 225 نانومتر. و قد امكن تعيين كلا من المركبين فى خليط من صورتهما النقية و المستحضرات الصيدلية و كذلك تم قياس الثباتية للمركبات محل الدراسة بعد تعرضهم لظروف تكسير مختلفة. وقد تمت مقارنة نتائج الطريقتين إحصائيا بالنتائج الدستورية و المرجعية التى جاءت متفقه معها.
    
     
 
       

Author Related Publications

  • Youstina Mekhail Metias Ibrahim, "Conductometric Determination of Tiemonium Methylsulfate, Alizapride Hydrochloride, Trimebutine Maleate using Rose Bengal, Ammonium Reineckate and Phosphotungstic Acid", Indian Journal of Advances in Chemical Science, 2016 More
  • Youstina Mekhail Metias Ibrahim, "Spectrophotometric Determination of Tiemonium Methyl Sulfate, Itopride Hydrochloride and Trimebutine Maleate via Ion Pair Complex Formation and Oxidation Reaction", Indian Journal of Advances in Chemical Science, 2015 More
  • Youstina Mekhail Metias Ibrahim, "Isocratic HPLC method for simultaneous determination of Tramadol hydrochloride and Pantoprazole sodium synthetic mixture in pure forms and injection formulations", Journal of Pharmacy Research, 2017 More
  • Youstina Mekhail Metias Ibrahim, "Development of green differential pulse voltammetric strategy for the determination of alfuzosin hydrochloride at pencil graphite and modified carbon paste electrodes", Slovene Chemical Society, 2023 More
  • Youstina Mekhail Metias Ibrahim, "High - throughput spectrofluorimetric approach for one-step, sensitive, and green assays of alfuzosin hydrochloride using a 96-well microplate reader: Application to tablet formulations and human urine", Elsevier, 2022 More

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