Prediction of high-risk oesophageal varices in patients with compensated cirrhosis using albumin-bilirubin-platelet score

Faculty Medicine Year: 2022
Type of Publication: ZU Hosted Pages:
Authors:
Journal: European Journal of Gastroenterology and Hepatology Wolters Kluwer Health, Inc. Volume:
Keywords : Prediction , high-risk oesophageal varices , patients with    
Abstract:
Background: Despite the fact that endoscopy is the gold standard for screening of high-risk varices (HRVs) in patients with compensated cirrhosis, it is invasive, costly and not necessary for all patients. So, noninvasive tests can replace endoscopy. We aimed at evaluating the albumin-bilirubin-platelet (ALBL-PLT) score as a noninvasive test in predicting HRVs in compensated cirrhotic patients versus Baveno VI and extended Baveno VI criteria. Methods: patients with compensated cirrhosis (n = 204) were included. Laboratory parameters, esophagogastroduodenoscopy (EGD) and liver stiffness measurement by transient elastography were done. Classification of patients according to the status of HRVs was done. We compared both groups on the basis of ALBL-PLT score, Baveno VI and extended Baveno VI criteria. Results: Among the total patients, 96/204 (47%) patients had HRVs. They have higher liver stiffness measurement than those without HRVs (33 ± 13.1 versus 19.3 ± 8.25, CI, −19.94, −7.31, P value <0.001). Also, all HRVs patients have an ALBL-PLT score of more than 3. The area under the receiver operating characteristic curve for the ALBL-PLT score is higher than that for Baveno VI and extended Baveno VI criteria (0.894 versus 0.722 and 0.792, respectively). Conclusion: ALBL-PLT score of more than three has a good predictive value in predicting HRVs among compensated cirrhotic patients.
   
     
 
       

Author Related Publications

  • Ahmed Lotfy Mohamed Zaki Sharf, "Hepatitis C virus infection could be a risk factor for adult-onset vitiligo in Egyptian patients: A cross-sectional study", Wiley, 2022 More
  • Ahmed Lotfy Mohamed Zaki Sharf, "Evaluation of Thyroid Functions in Cirrhotic Patients with Refractory Ascites", Zagazig University. Faculty of Medicine. Endemic and Tropical Medicine Department, 2022 More
  • Ahmed Lotfy Mohamed Zaki Sharf, "Optimality of 2-week Versus 4-week Intervals in Secondary Prophylaxis of Bleeding by Endoscopic Esophageal Variceal Ligation", Zagazig University. Faculty of Medicine. Endemic and Tropical Medicine Department, 2023 More
  • Ahmed Lotfy Mohamed Zaki Sharf, "Microscopic Colitis in Patients with Unexplained Chronic Watery non-Bloody Diarrhea: A Cross Sectional Study", Zagazig University. Faculty of Medicine. Endemic and Tropical Medicine Department, 2022 More
  • Ahmed Lotfy Mohamed Zaki Sharf, "Prognostic Roles and Survival Benefits of Endoscopic Resection Versus Surgical Resection in the Management of Malignant Colon Polyps", Thieme, 2023 More

Department Related Publications

  • Halle Ismail Mouhammed, "Impact Of Treatment Of Intestinal Parasites On The Activity Of Ulcerative Colitis أثر علاج الطفيليات المعوية على نشاط مرضى التهاب القولون المتقرح", جامعة الزقازيق, 2013 More
  • Halle Ismail Mouhammed, "Soluble Triggering Receptor Expressed On Myeloid Cells-1 As A Diagnostic Tool For Acute Bacterial Meningitis الصورة الذائبة لمستقبلات الحث الظاهرة على الخلايا الميلودية -1 كأداة تشخيصية للالتهاب السحائى البكتيرى الحاد", مجلة الجمعية المصرية للميكروبيولوجيا الطبية, 2010 More
  • Mohamed Ahmed Mohamed Suleiman Saraya, "Prednisolone Can Prevent Post-Herpetic Neuralgia in Post-Kidney Transplant Recipient بريدنيزلون يستطيع أن يمنع الألم العصبي التالى للهربس فى مرضى زراعة الكلى", Afro-Egyptian Journal of Infectious and Endemic Diseases, 2016 More
  • Mohamed Mohamed Refaei, "Is Serum Ferritin a Suitable Predictor of Treatment Outcomes in Chronic Hepatitis C Patients Treated with Interferon–Ribavirin Combined Therapy?", International Journal of Advanced Research, 2014 More
  • Abeer Hessien Abdelkader Abdelaziz, "Efficacy and Adverse Effects of Sofosbuvir plus Daclatasvir Therapy in Chronic HCV Patients in Sharkia Governorate, Egypt", Zagazig University, Faculty of Medicine, Hepatology, Gastroenterology, Infectious and Tropical Diseases Department, 2018 More
Tweet