Vitamin D receptor gene FokI polymorphism in Egyptian children
and adolescents with SLE: A case-control study

Faculty	Medicine	Year:	2017
Type of Publication:	ZU Hosted	Pages:
Authors:	Atef Mohamed Mohamed Khaliel Staff Zu Site Abstract In Staff Site
Journal:	Pediatric Lupus Pediatric Lupus	Volume:

Keywords :	Vitamin , receptor gene FokI polymorphism , Egyptian
Abstract:	: Childhood-onset systemic lupus erythematosus (cSLE) is a lifelong autoimmune disorder. The vitamin D receptor (VDR) gene is a potential candidate gene for cSLE susceptibility. In this study, we aimed to investigate the FokI polymorphism in the VDR gene in Egyptian children and adolescents with SLE, to determine whether this polymorphism could be a genetic marker for cSLE susceptibility or disease activity and we also measured the serum level of 25-hydroxyvitamin D [25(OH) D] to assess its relation to such polymorphism

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