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Risk assessment score for adverse pregnancy outcome in systemic lupus erythematosus patients.
Faculty
Medicine
Year:
2022
Type of Publication:
ZU Hosted
Pages:
Authors:
lobna Ismaeil Abdel Rehman kotb
Staff Zu Site
Abstract In Staff Site
Journal:
Egyptian Rheumatology and Rehabilitation springer
Volume:
Keywords :
Risk assessment score , adverse pregnancy outcome
Abstract:
Abstract Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune multisystem dihe criteria for SLE according to thsease that mainly affects females of childbearing age. SLE still possesses risks during pregnancy that lead to poor maternal and fetal outcomes. The objectives of the study were to identify factors associated with unfavorable pregnancy outcomes and develop a predictive risk score for adverse pregnancy outcomes in patients with SLE. Results: The main predictive factors associated with adverse pregnancy outcomes among lupus patients in multiple linear regression were an absence of remission for at least 6 months before conception, preexisting lupus nephritis, active disease at conception, C3 hypocomplementemia, and antiphospholipid antibody syndrome. Each predictor is assigned a weighted point score, and the sum of points represents the risk score. The area under the receiver operating characteristic curve (ROC) was 0.948 (95% confidence interval, 0.908–0.988), suggesting that the score had strong discriminatory power for adverse pregnancy outcomes. Conclusions: In this study, a predictive model with a risk score classification for adverse pregnancy outcomes in SLE patients was developed. This could help rheumatologists identify high-risk pregnant patients for better disease monitoring and management, resulting in better maternal/fetal outcomes.
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lobna Ismaeil Abdel Rehman kotb, "Impact of ultrasonography detected quadriceps calcific tendinopathy on pain and function in patients with primary knee osteoarthritis", Page press publication, 2021
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lobna Ismaeil Abdel Rehman kotb, "Predictors of admission to intensive care unit among systemic lupus erythematosus patients: prospective study", Springer, 2022
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lobna Ismaeil Abdel Rehman kotb, "Assessment of Validity and Reliability of an Arabic Version of Chronic Pain Acceptance Questionnaire in Rheumatic Disease Patients.", Turkish physiotherapy Association, 2021
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lobna Ismaeil Abdel Rehman kotb, "Ultrasonographic assessment of peripheral enthesopathy in early psoriatic arthritis and its correlation to serum levels of IL-23.", Anka publisher, 2022
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lobna Ismaeil Abdel Rehman kotb, "Effect of Anxiety and Depression on Functional Assessment of Knee Osteoarthritic Patients.", Ubiquity Press, 2021
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Department Related Publications
Wafaa Kamal Fattouh Mustafa Makram, "Impact of home exercise program on self-efficacy and quality of life among primary knee osteoarthritis patients: a randomized controlled clinical study", Springer, 2021
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Wafaa Kamal Fattouh Mustafa Makram, "Correlation between Relative Expression of IL 17 and PERP in Rheumatoid Arthritis Patients and Disease Activity", Modern Commercial Press, 2019
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Amany Mohamed Ibrahim Mouhmmed, "Association of Tumor Necrosis Like factor 1 A (TL1A) and its Decoy Receptor (DcR3) with The Disease Activity and Autoantibody Production in Rheumatoid Arthritis Patients.", Modern Commercial Press, 2019
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lobna Ismaeil Abdel Rehman kotb, "The Relation between Plasma Complemant 4 d and Disease Activity in Systemic Lupus Erythematosus Patients at Zagazig University Hospitals", Hampstead Psychological Associate, 2020
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Nahla Mohamed El Shahat AbdulAal, "INFLUENCE OF LEPTIN IN THE DEVELOPMENT OF OSTEOPOROSIS; CLINICAL, SEROLOGICAL AND RADIOLOGICAL STUDY.", لايوجد, 1900
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