Field trials were conducted in El- Salhia, Sharkia governorate, to assess the effectiveness of insecticides (imidaclopride, lambdacyhalothrin, and abamectin) against the two-spotted spider mite, Tetranychus urticae, on cucumber crops. The trial used a andomised complete block design (RCBD) with three treatments: T1: abamectin, T2: lambda-cyhalothrin, T3: imidaclopride, and control, which was repeated three times. At varied harvest intervals of (2h), 1, 3, 5, 7, 9-, 11-, 13-, and 15- days following insecticide applications, residues and abamectin dissipation were measured. The insecticide's persistence, dissipation, half-life value, and safe harvest interval in cucumber were estimated. Additionally, the effects of abamectin residues on various quality indices (total soluble sugars, glucose, acidity, total soluble solids, ascorbic acid, -carotene, dry matter, and protein) were assessed in the last three samples (7 and 15 days after applications). The results revealed that all the treatments reduced the two-spotted spider populations. Furthermore, the results showed that the treatments sprayed with abamectin gave the highest reduction percentage (96.32%), followed by lambda-cyhalothrin (92.22%) and imidaclopride (76.93%). The halflife (t12) values in cucumber fruits were 2.99 days, and the loss percentages of initial deposits in cucumber fruits were 8.96 mg/ kg. In conclusion, we encourage farmers to use abamectin according to the Ministry of Agriculture recommendation in combating T. urticae, in integrated pest management, as cucumbers can be safely consumed after 7 days of abamectin treatment.