CDK4/6 inhibitors in advanced breast cancer, what is beyond?

Faculty Medicine Year: 2019
Type of Publication: ZU Hosted Pages:
Authors:
Amarallah Abdelmoneim Mohamed Sayed
Journal: Oncology Reviews PAGEPress, Italy Volume:
Keywords : CDK4/6 inhibitors , advanced breast cancer, what    
Abstract:
Resistant to hormonal treatment considered the main clinical challenge in the management of advanced breast cancer (ABC). The use of CDK4/6 inhibitors (CDK4/6I) may change the treatment landscape. In this mandated review, we will focus on the applicable role of CDK4/6I in the management of HR+/HER2- ABC, mechanisms of resistance, and promising future implementation.
    
     
 
       

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