This paper presents a computational finite element model to study and analyze vibrations and stresses of regularly perforated rotated beams considering different perforation configurations, for the first time. Both regular circular and squared perforation configurations are considered. The geometry of the perforated beam is modelled using shell finite elements. The finite elements equations of motion are derived for a straight perforated cantilevered beam with a symmetrical cross section. The proposed computational procedure is checked by comparing the obtained results with the available results in the literature and an excellent agreement is observed. The free vibration response, as well as stress distributions throughout the beam, are investigated. The obtained results reveal that the perforation configuration, as well as the rotating speed, have remarkable effects on the dynamics and stress distributions of the rotating perforated beams.