Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Combination of oral methotrexate and oral mini-pulse dexamethasone vs either agent alone in vitiligo treatment with follow up by dermoscope
Faculty
Medicine
Year:
2020
Type of Publication:
ZU Hosted
Pages:
Authors:
Mohamed Ibrahim Abdel Razek ganayny
Staff Zu Site
Abstract In Staff Site
Journal:
dermatologic therapy wiley
Volume:
Keywords :
Combination , oral methotrexate , oral mini-pulse dexamethasone
Abstract:
This study aimed to compare the efficacy and safety of oral methotrexate (MTX) and oral mini-pulse (OMP) dexamethasone alone and in combination in the treatment of vitiligo. A total of 42 patients with vitiligo were included in the study. The patients were treated for three months and randomly assigned into three groups including 14 patients each: group A received oral MTX, group B received OMP dexamethasone, and group C received a combination of both. Follow-up was performed using digital photographs, Vitiligo European Task Force score, and dermoscopy. Disease extension significantly decreased in group C compared with that in groups A (P < .001) and B (P < .05). The frequency of intralesional pigmentation significantly increased (P < .05) in groups A and C and decreased (P < .05) in group B posttreatment noted using a dermoscope. Moreover, the frequency of micro-Koebner's phenomenon and starburst pattern significantly decreased (P < .05) in groups B and C and that of tapioca sago in group C only posttreatment.
Author Related Publications
Mohamed Ibrahim Abdel Razek ganayny, "Risk and severity of psoriasis vulgaris in relation to angiotensin II type 1 receptor gene polymorphism and metabolic syndrome", Dove press, 2019
More
Mohamed Ibrahim Abdel Razek ganayny, "Serum TSLP is a potential biomarker of psoriasis vulgaris activity", Dove press, 2019
More
Mohamed Ibrahim Abdel Razek ganayny, "Soluble CD27 and MIF as possible serum biomarkers of vitiligo activity in Egyptian patients in Sharkia Governorate", page press, 2019
More
Mohamed Ibrahim Abdel Razek ganayny, "Role of Tumor Necrosis Factor Alpha and Basic Fibroblast Growth Factor in the Pathogenesis of Vitiligo:An Immunohistochemical study before and after melanocyte transfer by sandpaper technique", ZUMJ, 2015
More
Mohamed Ibrahim Abdel Razek ganayny, "Role of Tumor Necrosis Factor Alpha and Basic Fibroblast Growth Factor in the Pathogenesis of Vitiligo:An Immunohistochemical study before and after melanocyte transfer by sandpaper technique", ZUMJ, 2015
More
Department Related Publications
Eman Abdelgawad Nasr Noufal, "Diagnosis of febrile ulceronecrotic Mucha- Habermann disease: strict clinical criteria are imperative", Correspondence Clinical Letter, 2016
More
Fatheah Mohammed Ahmed Abdullah khattab, "Evaluation of serum periostin level in atopic dermatitis patients", Wolters Kluwer - Medknow, 2018
More
Enayat Mohamed Elsayed Atwa, "Review of narrowband ultraviolet B radiation in vitiligo", © 2016 Baishideng Publishing Group Inc., 2016
More
Enayat Mohamed Elsayed Atwa, "Review of narrowband ultraviolet B radiation in vitiligo", © 2016 Baishideng Publishing Group Inc., 2016
More
Enayat Mohamed Elsayed Atwa, "Review of narrowband ultraviolet B radiation in vitiligo", © 2016 Baishideng Publishing Group Inc., 2016
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف