Evaluation of the efficacy and safety of deferiprone compared with deferasirox in paediatric patients with transfusion-dependent haemoglobinopathies (DEEP-2): a multicentre, randomised, open-label, non-inferiority, phase 3 trial

Faculty Medicine Year: 2020
Type of Publication: ZU Hosted Pages:
Authors:
Laila Metwally Ibrahim Sharif
Journal: lancet Haematology -Elsevierlancet Haematology Volume:
Keywords : Evaluation , , efficacy , safety , deferiprone compared with    
Abstract:
Background: Transfusion-dependent haemoglobinopathies require lifelong iron chelation therapy with one of the three iron chelators (deferiprone, deferasirox, or deferoxamine). Deferasirox and deferiprone are the only two oral chelators used
    
     
 
       

Author Related Publications

  • Laila Metwally Ibrahim Sharif, "18. Factors associated with delayed cancer diagnosis in egyptian children.", Clin Med Insights Pediatr, 2015 More
  • Laila Metwally Ibrahim Sharif, "serum trace elements in obese Egyptian children: a case -control study", BioMed Centr, 2014 More
  • Laila Metwally Ibrahim Sharif, "Biomarkers and early detection of late onset anthracycline-induced cardiotoxicity in children", W.S.&son Ltd 2012, 2012 More
  • Laila Metwally Ibrahim Sharif, "Progressive Familial Intrahepatic Cholestasis Type 3: a Novel Mutation in a Saudi Child", W, 2013 More
  • Laila Metwally Ibrahim Sharif, "Study of Non–organ‑specific Antibodies in Children with Genotype 4 Chronic Hepatitis C", Wolters kluwer/medhnow, 2013 More

Department Related Publications

  • Laila Metwally Ibrahim Sharif, "Egyptian pediatric guidelines for the management of childhood venous thromboembolism: the adapted methodology: a limited resource country perspective", thrombosis journal, 2025 More
  • Marwa Zakaria Mohammed Mustafa, "Egyptian pediatric guidelines for the management of childhood venous thromboembolism: the adapted methodology: a limited resource country perspective", thrombosis journal, 2025 More
  • Mervat Abdullah Hisham Hisham, "Egyptian pediatric guidelines for the management of childhood venous thromboembolism: the adapted methodology: a limited resource country perspective", thrombosis journal, 2025 More
  • Laila Metwally Ibrahim Sharif, "Glanzmann thrombasthenia: a multi-center study of demographics, clinical spectrum, and treatment efficacy", Springer- European journal of pediatrics, 2025 More
  • Salah Aldin Mohamed Elmorshedy, "Metabolic screening and its impact in children with nonsyndromic intellectual disability", Neuropsychiatric Disease and Treatment, 2017 More
Tweet