ABSTRACT Background: Mulberry silkworm, Bombyx mori L. is one of the most economically important insect because its production of silk cocoons which interfere with many important industries. Diseases of the silkworm, B. mori such as viral, bacterial, fungal and protozoan pathogens seriously affect their cocoon production. Bacterial and fungal pathogens independently cause the highest cocoon loss, so the use of botanicals is considered an important strategy to control diseases of silkworm. Results: The artificially infected silkworm, B. mori larvae with Bacillus thuriengiensis when treated with concentrations of 2 and 3% of black cumin seed and basil leaves extracts increased significantly larval weight and decreased larval mortality. In addition, 3% basil leaves extract and 1% of black cumin seed increased pupal weight. Cocoon weight and cocoon shell weight increased significantly by 3% basil leaves extract treatment. All tested concentrations of black cumin seed extract increased the silk ratios of the resulted cocoons as compared to the infected control. For technological parameters, all tested extracts at 3 % concentration caused the highest silk filament length; meanwhile control larvae recorded the highest silk filament weight and size. Regarding the mulberry silkworm, B. mori artificially infested with conidial solution of Beauveria bassiana when treated with all concentrations of the tested plants showed an enhancement in larval weight, pupal weight, cocoon weight, cocoon shell weight, silk filament length, and filament weight and reduced the larval mortality percentage. The highest silk filament size were recorded for the control group Conclusions: Tested concentrations of Morus alba, Ocimum basilicum leaves extracts and Nigella sativa seeds extract have suppressed the bacterial and fungal disease spread when used three times through both 4th and 5th larval instars. Moreover, the biological characters and technological traits enhanced by using of these extracts, so it can be used in sericulture for improving cocoon crop quality and quantity. Key words: Bombyx mori L., Bacillus thuriengiensis, Beauveria bassiana, artificially infection, biology, technology, silk filament