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Circulating methylated RUNX3 and SFRP1 genes as a noninvasive panel for early detection of colorectal cancer
Faculty
Medicine
Year:
2019
Type of Publication:
ZU Hosted
Pages:
Authors:
Ahmed Mohamed Ahmed Yehia
Staff Zu Site
Abstract In Staff Site
Journal:
European Journal of Gastroenterology & Hepatology European Journal of Gastroenterology & Hepatology
Volume:
Keywords :
Circulating methylated RUNX3 , SFRP1 genes , , noninvasive
Abstract:
This study was performed to evaluate the homogeneity of transcription factor-linked factor 3 (RUNX3) and associated protein-linked protein 1 (SFRP1) genes in tissues and serum samples from patients with colorectal cancer (CRC), adenomyosis, and control group. To clarify the relationship between methylation and the results indicate the possibility of using the homogeneity of the RUNX3 and SFRP1 genes in serum as a non-invasive indicator for diagnosing colon malignancies.
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