The anatomical variations of the intra-cranial ve-nous dural sinuses must be put in consideration in diagnosing magnetic resonance venography (MRV) to avoid the diagnostic pitfalls resulting from over-diagnosis of cerebral venous dural sinus oc-clusion or thrombosis. The available data regard-ing the age and sex difference of the magnetic res-onance venography (MRV) anatomical variations is still limited. A retrospective study is done for 500 patients ranging from 20 to 70 years. Only 363 patients (142 males and 221 females) were includ-ed in our final analysis: all have normal MRI brain & posterior fossa. Magnetic resonance venography (MRV) is done to detect the presence or absence of the transverse venous dural sinuses and to de-tect any age- or sex-related differences. Also 64 dry Egyptian skulls (41 males and 23 females) were employed to detect symmetry of transverse sulcus and to determine age and sex difference. Hypoplastic left transverse sinus was by far the commonest asymmetrical transverse sinus vari-ants representing 22.0% of total: it was noted in 38 male and 38 female. Even if the asymmetrical transverse sinus is more common in females, there is no significant difference between both gen-ders. In the dry skull, symmetrical transverse sul-cus was observed in 67.2% of total, while asym-metrical transverse sulcus was recorded in 32.8% of total, which were more observed in female skull 17.2% of total with no significant difference