Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Poly (vinyl chloride) matrix membrane sensors for the quantification of olopatadine and oxeladine in pharmaceutical preparations and human plasma
Faculty
Science
Year:
2019
Type of Publication:
ZU Hosted
Pages:
Authors:
Mohamed Alaa Addeen Fathy Mohamed
Staff Zu Site
Abstract In Staff Site
Journal:
ُMicrochemical Journal USA
Volume:
Keywords :
Poly (vinyl chloride) matrix membrane sensors
Abstract:
Two novel potentiometric sensors were developed for the quantification of olopatadine hydrochloride and oxeladine citrate in pure forms, pharmaceutical preparations and human plasma. The both sensors were fabricated on incorporating the olopatadine and oxeladine tetraphenylborate ion-pairs as electroactive materials in plasticized poly (vinyl chloride) matrix membranes with o-nitrophenyl octyl ether. They displayed Nernstian and near Nernstian responses over the concentration ranges of 1.0×10−5–1.0×10−2 mol L−1 oxeladine and olopatadine with cationic slopes of 60 and 50 mV decade−1, respectively. Detection limits were reported to be 4.4×10−6 and 5.0×10−6 mol L−1 while the response times were 3.0 and 18 s for oxeladine and olopatadine, respectively. The useful ranges of pH were 2.5–8.5 and 3.0–4.5 for oxeladine and olopatadine, respectively. The life extents were long (3 months) for both sensors. The sensors were successfully used for the assay of oxeladine and olopatadine in pharmaceutical dosage forms with a recovery of 100.0% for both drugs. Also the oxeladine
Author Related Publications
Mohamed Alaa Addeen Fathy Mohamed, "Lead(II) Potentiometric Sensor Based on1,4,8,11-Tetrathiacyclotetradecane Neutral Carrier and LipophilicAdditives", USA, 2008
More
Mohamed Alaa Addeen Fathy Mohamed, "Liquid Chromatographic and Potentiometric Methods for Determinations of Clopidogrel", USA, 2008
More
Mohamed Alaa Addeen Fathy Mohamed, "Novel Sensors for Batch and Flow Injection Analysis of Histamine Based on Crown Ethers", USA, 2012
More
Mohamed Alaa Addeen Fathy Mohamed, "Recognition and Quantification of Some Monoamines Neurotransmitters", USA, 2016
More
Mohamed Alaa Addeen Fathy Mohamed, "New Potentiometric and Spectrophotometric Methods for the Determination of Dextromethorphan in Pharmaceutical Preparations", Japan, 2014
More
Department Related Publications
Maher Abdul Rahman Shams al-Din Safty, "synthesis and behaviour of 4-(4-chloro-3-methyl) phenyl- (2H)-phthalazinone towards some elecrophiles and nucleophiles", لايوجد, 1900
More
Wael Salah AbdelHalim, "Artificial polarization effects on F_A1^∶Sr^(2+), lasers and NO interactions at NaCl (001) surface: First principles calculations", elsevier, 2007
More
Wael Salah AbdelHalim, "Ab initio defect based model for laser light generation and color image formation at the flat, edge and corner surfaces of AgBr: F_A1^∶Cs^+ and F_A2^∶Li^+", elsevier, 2005
More
Hamdy Aldedamony , "Effect of delayed addition time of synthesized SSPF condensate on the durability of sulphate resisting cement pastes incorporating micro-silica", Constructing and building materials, 2014
More
Hamdy Aldedamony , "Behavior of delayed addition time of SNF superplasticizer on microsilica-sulphate resisting cements.", Ceramics – Silikáty, 2014
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف