Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids.

Faculty Pharmacy Year: 2019
Type of Publication: ZU Hosted Pages: 1-12
Authors:
Tarek Mohamed Salah Rashad
Journal: Chemical Biology and Drug Design Wiely Volume:
Keywords : Design, synthesis, antimicrobial, , , gyrase inhibitory properties    
Abstract:
A series of new fluoroquinolone conjugates 8a–g and 9a–f were synthesized via benzotriazole‐mediated synthetic approach with good yield and purity. Some of the synthesized analogs exhibited significant antibacterial properties against Esche
    
     
 
       

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