Novel benzenesulfonamide and 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives as potential selective COX-2 inhibitors

Faculty Pharmacy Year: 2019
Type of Publication: ZU Hosted Pages: 372-382
Authors:
Amany Mohamed Mohamed Elmahmoudy Sanger
Journal: European Journal of Medicinal Chemistry ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER Volume:
Keywords : Novel benzenesulfonamide , 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives , potential selective    
Abstract:
Two new series of 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives containing either five membered heterocyclic rings or aryl hydrazones were synthesized and evaluated for their in vitro COX-1/COX-2 inhibitory activity. In vivo anti-inf
    
     
 
       

Author Related Publications

  • Amany Mohamed Mohamed Elmahmoudy Sanger, "Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors", mdpi, 2022 More
  • Amany Mohamed Mohamed Elmahmoudy Sanger, "Synthesis, Antibacterial Evaluation, and Computational Studies of a Diverse Set of Linezolid Conjugates", mdpi, 2022 More
  • Amany Mohamed Mohamed Elmahmoudy Sanger, "Novel Benzyloxyphenyl Pyrimidine-5-Carbonitrile Derivatives as Potential Apoptotic Antiproliferative Agents", Bentham Science Publishers, 2022 More
  • Amany Mohamed Mohamed Elmahmoudy Sanger, "DOCKING, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL PYRAZOLINE DERIVATIVES AS POTENTIAL ANTIMICROBIAL AND ANTITUMOR AGENTS", www.wjpr.net, 2016 More
  • Amany Mohamed Mohamed Elmahmoudy Sanger, "SYNTHESIS OF NOVEL PYRIMIDINE AND FUSED PYRIMIDINE DERIVATIVES AND THEIR IN VITRO ANTIMICROBIAL AND CYTOTOXIC EVALUATION", www.wjpr.net, 2017 More

Department Related Publications

  • Tarek Mohamed Salah Rashad, "New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors", mdpi, 2021 More
  • Nader Elmaghawry Mostafa Abodeah, "Efficient synthesis of N-acylbenzotriazoles using tosyl chloride: en route to suberoylanilide hydroxamic acid (SAHA)", ARKIVOC, 2016 More
  • Tarek Mohamed Salah Rashad, "Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors", Taylor & Francis Group, 2022 More
  • Tarek Mohamed Salah Rashad, "Novel benzenesulfonamide and 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives as potential selective COX-2 inhibitors", ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2019 More
  • Hanan Abdelraziek Abdelfattah Ali Hamied, "Design synthesis and molecular modeling study of quinazolin 4(3H) ones with potential anti-inflammatory activity", لايوجد, 1900 More
Tweet