X-ray crystal structure of a 2-amino-3, 4-dihydroquinazoline 5-HT3 serotonin receptor antagonist and related analogs

Faculty Pharmacy Year: 2020
Type of Publication: ZU Hosted Pages: 761-770
Authors:
Ahmed Samy Abdelsamad Abdelkhalek hilal
Journal: Poultry Science international Volume: 98
Keywords : X-ray crystal structure , , 2-amino-3, 4-dihydroquinazoline 5-HT3    
Abstract:
Certain 2-amino-3,4-dihydroquinazolines bind at 5-HT3 serotonin receptors and act as antagonists (e.g. 6-chloro) whereas others bind with little to no affinity and lack functional activity (e.g. 8-chloro). The purpose of this investigation
   
     
 
       

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  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN-4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS", international, 2013 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Synthesis and biological screening of new derivatives of 2,3-dihydro quinazolin-4(1H)-one and benzotriazepin- 5(2H)-one for central nervous system activity", international, 2014 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "“Methylene Bridge” to 5-HT3 Receptor Antagonists Conformationally Constrained Phenylguanidines", American Chemical Society, 2018 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Probing of 2-Amino-6-Chloro-3,4-Dihydroquinazoline Hydrochloride At 5- HT3 Receptor", Scholars Research Library, 2018 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Probing of 2-Amino-6-Chloro-3,4-Dihydroquinazoline Hydrochloride At 5- HT3 Receptor", Scholars Research Library, 2018 More

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