"Immunological responses to PEGylated proteins: anti-PEG antibodies"

Faculty Pharmacy Year: 2019
Type of Publication: ZU Hosted Pages:
Authors:
Amr Selim Ahmed Ali Abu Lila
Journal: .Egypt. J. Food Sci Elsevier Volume:
Keywords : "Immunological responses , PEGylated proteins: anti-PEG antibodies"    
Abstract:
PEGylation, the covalent coupling of PEG chains to therapeutic proteins, is a commonly used technique for mitigating some pharmacokinetic (PK) limitations of protein therapeutics by improving their circulation half-lives. Nevertheless, in c
    
     
 
       

Author Related Publications

  • Amr Selim Ahmed Ali Abu Lila, "Activation of TLR9 by incorporated pDNA within PEG-coated lipoplex enhances anti-PEG IgM production", nature, 2014 More
  • Amr Selim Ahmed Ali Abu Lila, "Treatment of pulmonary arterial hypertension by vardenafil-solid dispersion lozenges as a potential alternative drug delivery system", Elsevier, 2020 More
  • Amr Selim Ahmed Ali Abu Lila, "Doxorubicin Embedded into Nanofibrillated Bacterial Cellulose (NFBC) Produces a Promising Therapeutic Outcome for Peritoneally Metastatic Gastric Cancer in Mice Models via Intraperitoneal Direct Injection", MDPI, 2021 More
  • Amr Selim Ahmed Ali Abu Lila, "Efficacy of SPG-ODN 1826 Nanovehicles in Inducing M1 Phenotype through TLR-9 Activation in Murine Alveolar J774A.1 Cells: Plausible Nano-Immunotherapy for Lung Carcinoma", MDPI, 2021 More
  • Amr Selim Ahmed Ali Abu Lila, "Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer", MDPI, 2021 More

Department Related Publications

  • Eman Gomaa Ahmed alsayed, "Albumin-Based Nanoparticles with Factorial Design as aPromising Approach for Remodeled Repaglinide: Evidence fromIn Silico, In Vitro, and In Vivo Evaluations (PDF) Albumin-Based Nanoparticles with Factorial Design as a Promising Approach for Remodeled Repaglinide: Evidence from In Silico, In Vitro, and In Vivo Evaluations. Available from: https://www.researchgate.net/publication/389711503_Albumin-Based_Nanoparticles_with_Factorial_Design_as_a_Promising_Approach_for_Remodeled_Repaglinide_Evidence_from_In_Silico_In_Vitro_and_In_Vivo_Evaluations#fullTextFileContent [accessed Mar 10 2026].", MDPI, 2025 More
  • Menatalla Mohammed Faisal, "Albumin-Based Nanoparticles with Factorial Design as aPromising Approach for Remodeled Repaglinide: Evidence fromIn Silico, In Vitro, and In Vivo Evaluations (PDF) Albumin-Based Nanoparticles with Factorial Design as a Promising Approach for Remodeled Repaglinide: Evidence from In Silico, In Vitro, and In Vivo Evaluations. Available from: https://www.researchgate.net/publication/389711503_Albumin-Based_Nanoparticles_with_Factorial_Design_as_a_Promising_Approach_for_Remodeled_Repaglinide_Evidence_from_In_Silico_In_Vitro_and_In_Vivo_Evaluations#fullTextFileContent [accessed Mar 10 2026].", MDPI, 2025 More
  • Amr Selim Ahmed Ali Abu Lila, "A Novel Platform for Cancer Vaccines: Antigen-Selective Delivery to Splenic Marginal Zone B Cells via Repeated Injections of PEGylated Liposomes", American Association, 2018 More
  • Menatalla Mohammed Faisal, "Bimodal Release Two-In-One Clonazepam Matrix Lozenge Tablets for Managing Anxiety-Related Disorders: Formulation, Optimization and In Vivo Evaluation", MDPI, Basel, Switzerland, 2022 More
  • Eman Gomaa Ahmed alsayed, "Bimodal Release Two-In-One Clonazepam Matrix Lozenge Tablets for Managing Anxiety-Related Disorders: Formulation, Optimization and In Vivo Evaluation", MDPI, Basel, Switzerland, 2022 More
Tweet