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multidrug resistance 1 genetic polymorphisms gene expression and prediction of chemotherapy response in breast cancer Egyptian patients
Faculty
Medicine
Year:
2014
Type of Publication:
ZU Hosted
Pages:
Authors:
Lamia Mahmoud Mohamed Kamel
Staff Zu Site
Abstract In Staff Site
Journal:
Med. J. Cairo Univ., The scientific journal of egyptian society of biochemistry and molecular biology
Volume:
Keywords :
multidrug resistance , genetic polymorphisms gene expression
Abstract:
Although anthracycline-based chemotherapy is a crucial treatment for breast cancer, its outcome is limited by the multidrug resistance MDR. Overexpression of P-glycoprotein (Pgp), a transmembrane active efflux transporter of various drugs a
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