Synthesis, heterocyclization and anti-tumour activity evaluation of some benzimidazole derivatives

Faculty Science Year: 2018
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Journal of Heterocyclic Chemistry USA Volume:
Keywords : Synthesis, heterocyclization and anti-tumour activity evaluation of some    
Abstract:
Methylbenzimidazole 1 is converted to imidazole acrylic acid 3 via cyclo condensation with chloral followed by hydrolysis. Compound 3 also obtained from the reaction of o-phenylenediamine with maleic anhydride. Treatment of 1 with SeO2
   
     
 
       

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