Probing of 2-Amino-6-Chloro-3,4-Dihydroquinazoline Hydrochloride At 5- HT3 Receptor

Faculty Pharmacy Year: 2018
Type of Publication: ZU Hosted Pages:
Authors:
Ahmed Samy Abdelsamad Abdelkhalek hilal
Journal: Der Pharmacia Lettre Scholars Research Library Volume:
Keywords : Probing , 2-Amino-6-Chloro-3,4-Dihydroquinazoline Hydrochloride , 5- HT3 Receptor    
Abstract:
2-amino-6-chloro-3,4-dihydroquinazoline Hydrochloride (2) is 5-HT3 receptor antagonist. The results viewed that monosubstitution and di-substitution of terminal amine lead to abolish binding affinity at 5-HT3 receptors and this was consiste
    
     
 
       

Author Related Publications

  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN-4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS", international, 2013 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Synthesis and biological screening of new derivatives of 2,3-dihydro quinazolin-4(1H)-one and benzotriazepin- 5(2H)-one for central nervous system activity", international, 2014 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "“Methylene Bridge” to 5-HT3 Receptor Antagonists Conformationally Constrained Phenylguanidines", American Chemical Society, 2018 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Probing of 2-Amino-6-Chloro-3,4-Dihydroquinazoline Hydrochloride At 5- HT3 Receptor", Scholars Research Library, 2018 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "X-ray crystal structure of a 2-amino-3, 4-dihydroquinazoline 5-HT3 serotonin receptor antagonist and related analogs", international, 2020 More

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