Synthesis, In vivo and In silico Evaluation of Novel 2,3-Dihydroquinazolin-4(1H)-one Derivatives as Potential Anticonvulsant Agents

Faculty Pharmacy Year: 2019
Type of Publication: ZU Hosted Pages: 343-352
Authors:
Hend Kather Abdelhakem Elhamalawy
Journal: Drug Development Research wiley Volume: 80
Keywords : Synthesis, , vivo , , silico Evaluation , Novel 2,3-Dihydroquinazolin-4(1H)-one    
Abstract:
In light of the pharmacophoric structural requirements for achieving anticonvulsant activity, a series of N-(1-methyl-4-oxo-2-un/substituted-1,2-dihydroquinazolin-3[4H]-yl)benzamide (4a-g) and N-(1-methyl-4-oxo-2-un/substituted-1,2-dihydroq
    
     
 
       

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  • Hend Kather Abdelhakem Elhamalawy, "Preclinical evaluation of Rad6 inhibition to overcome platinum resistance in ovarian cancer", AACR, 2016 More
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  • Hend Kather Abdelhakem Elhamalawy, "Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Anti-inflammatory Evaluation", WILEY interscience, 2010 More
  • Hend Kather Abdelhakem Elhamalawy, "Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity", springer link, 2013 More
  • Hend Kather Abdelhakem Elhamalawy, "Novel Inhibitors of Rad6 Ubiquitin Conjugating Enzyme: Design, Synthesis, Identification, and Functional Characterization", AACR publications, 2013 More

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