A Facile Synthesis of N- and O-alkylated Nicotinonitriles and its 2-methoxy 1,2,3 triazole Candidates as Potential Anticancer and Antimicrobial Agents

Faculty Science Year: 2018
Type of Publication: ZU Hosted Pages: 6-10
Authors:
Ahmed Heussein Mostafa
Journal: Der Pharma Chemica Elsiver Volume: 10
Keywords : , Facile Synthesis , , , O-alkylated Nicotinonitriles , , 2-methoxy 1,2,3 triazole    
Abstract:
A series of N- and O- alkylated nicotinonitriles was reported. Base mediate alkylation of nicotinonitriles 1a-c with chloroacetonitrile, allyl bromide and propargyl bromide produced N- and O- alkylated nicotinonitrile derivatives 3-6. Reac
    
     
 
       

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