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Synthesis, Anticonvulsant Activity, and SAR Study of Novel 4-Quinazolinone Derivatives
Faculty
Pharmacy
Year:
2017
Type of Publication:
ZU Hosted
Pages:
Authors:
Nada Abdasattar mohamed Noureddine
Staff Zu Site
Abstract In Staff Site
Journal:
Archiv der Pharmazie Wiley
Volume:
Keywords :
Synthesis, Anticonvulsant Activity, , , Study , Novel 4-Quinazolinone Derivatives
Abstract:
Series of N-(4-substitutedphenyl)-4-(1-methyl (or 1,2-dimethyl)-4-oxo-1,2-dihydroquinazolin-3(4H)-yl)-alkanamides (5a–j) and 4-chloro-N0-((1-methyl (or 1,2-dimethyl)-4-oxo-1,2-dihydroquinazolin-3(4H)-yl)alkaloyl)benzohydrazides (6a–f) were
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Nada Abdasattar mohamed Noureddine, "Design, synthesis and biological evaluation of novel quinazoline-2,4- diones conjugated with different amino acids as potential chitin synthase inhibitors", elsevier, 2018
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Nada Abdasattar mohamed Noureddine, "Design, computational studies, synthesis and in vitro antimicrobial evaluation of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues", springer nature, 2021
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Nada Abdasattar mohamed Noureddine, "Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation", MDPI, 2023
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Nada Abdasattar mohamed Noureddine, "Phenylalanyl tRNA synthetase (PheRS) substrate mimics: design, synthesis, molecular dynamics and antimicrobial evaluation", Royal Society of Chemistry, 2022
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Nada Abdasattar mohamed Noureddine, "Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation", MDPI, 2023
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Department Related Publications
Mansour Alsayed Mansour Abokol, "SYNTHESIS OF 3- SUBSTITUTED (6-BROMO-2-IMIDAZO {4, 5- B} PYRIDINYL) PROPIONIC ACID AS ANTIINFLAMMATORY, ANALGESIC, AND ANTIPYTRIC AGENTS", Zag. J. Pharm. Sci., Vol. 1 No. 1 Nov. Pp 129-139 June, 1993
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Mahmoud Mohamed Mohamed Sebaee, "Developing a High-performance Liquid Chromatography Method for Simultaneous Determination of Loratadine and its Metabolite Desloratadine in Human Plasma", benthamscience, 2020
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Noha Ibrahiem Elsayed Mohamed Zidain, "Developing a High-performance Liquid Chromatography Method for Simultaneous Determination of Loratadine and its Metabolite Desloratadine in Human Plasma", benthamscience, 2020
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Sobhi Mohamed Mahmoud Ibrahym, "47. Hplc determination of three cephalosporines (cefipime, ceftriaxone , cefotaxime) in their bulk and dosage form", Asian J .Pharm. Ana., 2014
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Ahmed Samy Abdelsamad Abdelkhalek hilal, "Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation", Taylor and francis, 2023
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