Synthesis, Anticonvulsant Activity, and SAR Study of Novel 4-Quinazolinone Derivatives

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Nada Abdasattar mohamed Noureddine
Journal: Archiv der Pharmazie Wiley Volume:
Keywords : Synthesis, Anticonvulsant Activity, , , Study , Novel 4-Quinazolinone Derivatives    
Abstract:
Series of N-(4-substitutedphenyl)-4-(1-methyl (or 1,2-dimethyl)-4-oxo-1,2-dihydroquinazolin-3(4H)-yl)-alkanamides (5a–j) and 4-chloro-N0-((1-methyl (or 1,2-dimethyl)-4-oxo-1,2-dihydroquinazolin-3(4H)-yl)alkaloyl)benzohydrazides (6a–f) were
   
     
 
       

Author Related Publications

  • Nada Abdasattar mohamed Noureddine, "Design, synthesis and biological evaluation of novel quinazoline-2,4- diones conjugated with different amino acids as potential chitin synthase inhibitors", elsevier, 2018 More
  • Nada Abdasattar mohamed Noureddine, "Design, computational studies, synthesis and in vitro antimicrobial evaluation of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues", springer nature, 2021 More
  • Nada Abdasattar mohamed Noureddine, "Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation", MDPI, 2023 More
  • Nada Abdasattar mohamed Noureddine, "Phenylalanyl tRNA synthetase (PheRS) substrate mimics: design, synthesis, molecular dynamics and antimicrobial evaluation", Royal Society of Chemistry, 2022 More
  • Nada Abdasattar mohamed Noureddine, "Inhibition of metallo-β-lactamases in carbapenem resistant Gram negative bacilli by omeprazole and pantoprazole", Makerere University Medical School, 2025 More

Department Related Publications

  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and biological activity of 2,5-diaryl-3-methyl-pyrimidino[4,5-c]quinolin-1(2H)-one derivatives", Elsevier, 2007 More
  • Kamel Abdelrehem Metwaly Bayomy, ". Synthesis, in-vitro Cytotoxicity, and a Preliminary Structure-Activity Relationship Investigation of Pyrimido[4,5-c]quinolin-1(2H)-ones", Wiley-Interscience, 2010 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Synthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazepine Derivatives for Biological Study " تشييد مشتقات جديدة من 1و3 بنزوديازين و1و3و4 بنزوتريازيبين وذلك للدراسة البيولوجية", 2024 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazepine Derivatives for Biological Study " تشييد مشتقات جديدة من 1و3 بنزوديازين و1و3و4 بنزوتريازيبين وذلك للدراسة البيولوجية", 2024 More
  • Mansour Alsayed Mansour Abokol, "Synthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazepine Derivatives for Biological Study " تشييد مشتقات جديدة من 1و3 بنزوديازين و1و3و4 بنزوتريازيبين وذلك للدراسة البيولوجية", 2024 More
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