Optimization of methotrexate loaded niosomes by Box–Behnken design: an understanding of solvent effect and formulation variability

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages: 1450-1459
Authors:
Journal: Drug Development and Industrial Pharmacy Drug Development and Industrial Pharmacy Volume: 9
Keywords : Optimization , methotrexate loaded niosomes , Box–Behnken design:    
Abstract:
Dermal drug delivery system which localizes methotrexate (MTX) in the skin is advantageous in topical treatment of psoriasis. The aim of the current study was to understand dilution effects and formulation variability for the potential form
   
     
 
       

Author Related Publications

  • Nagia] Ahmed Alameen Elmgrab, "Novel Aqueous solvent based method for protein based nanoparticles.", Association of Biotechnology and pharmacy ®., 2008 More
  • Nagia] Ahmed Alameen Elmgrab, "Modulation of Clonazepam Solubility using Solid Dispersion Technique Improves its Solubility and Bioavailability", A & V Publications India, 2012 More
  • Nagia] Ahmed Alameen Elmgrab, "Oestradiol permeation through human skin and silastic membrane: effects of propylene glycol and supersaturation", Elsevier B.V., 1995 More
  • Nagia] Ahmed Alameen Elmgrab, "Ocular controlled delivery of brimonidine using liposomes as a particulate carrier", faculty of pharmac,y zagazig university, 2001 More
  • Nagia] Ahmed Alameen Elmgrab, "Enhancement of Antibacterial Activity of Tetracycline Hydrochloride By Niosomal Encapsulation", the faculty of pharmacy zagazig university, 2005 More

Department Related Publications

  • Eman Gomaa Ahmed alsayed, "Albumin-Based Nanoparticles with Factorial Design as aPromising Approach for Remodeled Repaglinide: Evidence fromIn Silico, In Vitro, and In Vivo Evaluations (PDF) Albumin-Based Nanoparticles with Factorial Design as a Promising Approach for Remodeled Repaglinide: Evidence from In Silico, In Vitro, and In Vivo Evaluations. Available from: https://www.researchgate.net/publication/389711503_Albumin-Based_Nanoparticles_with_Factorial_Design_as_a_Promising_Approach_for_Remodeled_Repaglinide_Evidence_from_In_Silico_In_Vitro_and_In_Vivo_Evaluations#fullTextFileContent [accessed Mar 10 2026].", MDPI, 2025 More
  • Menatalla Mohammed Faisal, "Albumin-Based Nanoparticles with Factorial Design as aPromising Approach for Remodeled Repaglinide: Evidence fromIn Silico, In Vitro, and In Vivo Evaluations (PDF) Albumin-Based Nanoparticles with Factorial Design as a Promising Approach for Remodeled Repaglinide: Evidence from In Silico, In Vitro, and In Vivo Evaluations. Available from: https://www.researchgate.net/publication/389711503_Albumin-Based_Nanoparticles_with_Factorial_Design_as_a_Promising_Approach_for_Remodeled_Repaglinide_Evidence_from_In_Silico_In_Vitro_and_In_Vivo_Evaluations#fullTextFileContent [accessed Mar 10 2026].", MDPI, 2025 More
  • Abdullah Mohammed Abdullah Ayub, "INTRANASAL MICROEMULGEL AS SURROGATE CARRIER TO ENHANCE LOW ORAL BIOAVAILABILITY OF SULPIRIDE", Innovare Academic Sciences Pvt Ltd, 2016 More
  • Marwa Helmy Abedullahh, "INTRANASAL MICROEMULGEL AS SURROGATE CARRIER TO ENHANCE LOW ORAL BIOAVAILABILITY OF SULPIRIDE", Innovare Academic Sciences Pvt Ltd, 2016 More
  • Mahmoud Abdalghany Mahmoud Mahdy, "INTRANASAL MICROEMULGEL AS SURROGATE CARRIER TO ENHANCE LOW ORAL BIOAVAILABILITY OF SULPIRIDE", Innovare Academic Sciences Pvt Ltd, 2016 More
Tweet