Synthesis and anticancer activity of novel quinazolinone-based rhodanines

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Kamel Abdelrehem Metwaly Bayomy
Journal: Chemistry Central Journal Springer Volume:
Keywords : Synthesis , anticancer activity , novel quinazolinone-based rhodanines    
Abstract:
Background: Rhodanines and quinazolinones have been reported to possess various pharmacological activities. Results: A novel series of twenty quinazolinone-based rhodanines were synthesized via Knoevenagel condensation between 4-[3-(substit
    
     
 
       

Author Related Publications

  • Kamel Abdelrehem Metwaly Bayomy, "Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study", ELSEVIER, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone‑based rhodanines", Springer Open, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", taylor and francis online, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl t RNA synthetase: design ,synthesis and antibacterial activity against clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Novel 2,4- thiazolidinediones: synthesis, in vitro cytotoxic activity, and mechanistic investigation", ُُُُElsevier, 2017 More

Department Related Publications

  • Kamel Abdelrehem Metwaly Bayomy, "Pyrimido[4,5-c]quinolin-1(2H)-ones as a novel class of antimitotic agents: synthesis and in vitro cytotoxic activity", Elsevier, 2007 More
  • Mahmoud Mohamed Mohamed Sebaee, "Potential Role of Sulfur Nanoparticles as Antitumor and Antioxidant in Mice", Scholars Research Library, 2018 More
  • Alsayed Mohamed Mansour Lashen , "Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents", Elsevier, 2016 More
  • Mansour Alsayed Mansour Abokol, "Synthesis of certain Arylalkanoic Acid Derivatives of pharmacutical Interest", لايوجد, 1900 More
  • Ahmed Gamal Mohamed Abdallah Eissa, "Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation", MDPI, 2023 More
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