β-arrestin-mediated signaling improves the efficacy of therapeutics.

Faculty Pharmacy Year: 2012
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Journal of Pharmacological science J-STAGE Volume:
Keywords : β-arrestin-mediated signaling improves , efficacy , therapeutics.    
Abstract:
β-Arrestins (β-arrestin-1 and β-arrestin-2) were first identified as proteins that have the ability to desensitize G protein-coupled receptors (GPCRs). However, it has recently been found that β-arrestins can activate signaling pathways ind
   
     
 
       

Author Related Publications

  • Eslam Ahmed Abdelhamid ebrahiem, "GSK-3 heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy", Am J Physiol Heart Circ Physiol, 2016 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Sildenafil protects against bile duct ligation induced hepatic fibrosis in rats: Potential role for silent information regulator 1 (SIRT1)", ُElsevier, 2017 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Hesperidin protects against stress induced gastric ulcer through regulation of peroxisome proliferator activator receptor gamma in diabetic rats", ELSEVIER, 2018 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Ameliorative effects of clonidine on ethanol induced kidney injury in rats: Potential role for imidazoline-1 receptor.", zagizag, 2018 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Carvedilol protects against hepatic ischemia/reperfusion injury in high-fructose/high-fat diet-fed mice: Role of G protein-coupled receptor kinase 2 and 5", Science direct, 2019 More

Department Related Publications

  • Mona Fouad Mahmoud Abdelaziz, "Ammodaucus leucotrichus Coss. & Dur. Attenuates acrylamide-induced hepatic injury through enhancing autophagy and inhibiting endoplasmic reticulum stress and apoptotic signaling", ELSEVIER, 2024 More
  • Shimaa Mostafa Mostafa Elshazly, "Doxazosin down-regulates sodium-glucose cotransporter-2 and exerts a renoprotective effect in rat models of acute renal injury", wiley, 2019 More
  • Eslam Ahmed Abdelhamid ebrahiem, "GSK-3 heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy", Am J Physiol Heart Circ Physiol, 2016 More
  • Samar Abdelmigeed Mohamed Rezk, "1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study", elsevier, 2018 More
  • Mona Fouad Mahmoud Abdelaziz, "Rimonabant ameliorates hepatic ischemia/reperfusion injury in rats: Involvement of autophagy via modulating ERK-and PI3K/ AKT-mTOR pathways", Elsevier, 2021 More
Tweet