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The selective 5-LOX inhibitor 11-keto-β-boswellic acid protects against myocardial ischemia reperfusion injury in rats: involvement of redox and inflammatory cascades
Faculty
Pharmacy
Year:
2012
Type of Publication:
ZU Hosted
Pages:
Authors:
Shimaa Mostafa Mostafa Elshazly
Staff Zu Site
Abstract In Staff Site
Journal:
Naunyn-Schmiedeberg's Arch Pharmacol Naunyn-Schmiedeberg's Arch Pharmacol
Volume:
Keywords :
, selective 5-LOX inhibitor 11-keto-β-boswellic acid protects against
Abstract:
Myocardial ischemia induces 5-lipoxygenase (LOX) translocation and leukotriene production in the heart. Leukotrienes increase inflammatory responses aggravating, thereby, ischemia–reperfusion (I/R) injury. This study aimed to investigat
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