Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ12,14-Prostamide J2, as a Selective Antitumor Therapeutic

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Molecular Cancer Therapeutics American Associatiion of Cancer Research Volume:
Keywords : Synthesis , Evaluation , , Novel Prostamide, 15-Deoxy, Δ12,14-Prostamide    
Abstract:
15-deoxy, Δ12,14-prostaglandin J2-ethanolamide, also known as 15-deoxy, Δ12,14-prostamide J2 (15d-PMJ2) is a novel product of the metabolism of arachidonoyl ethanolamide (AEA) by COX-2. 15d-PMJ2 preferentially induced cell death and apoptos
   
     
 
       

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