Synthesis, antibacterial properties and 2D-QSAR studies of quinolone-triazole conjugates

Faculty Pharmacy Year: 2018
Type of Publication: ZU Hosted Pages: 1524-1534
Authors:
Amany Mohamed Mohamed Elmahmoudy Sanger
Journal: European Journal of Medicinal Chemistry ElSevier Volume: 2018
Keywords : Synthesis, antibacterial properties , 2D-QSAR studies , quinolone-triazole    
Abstract:
A set of 1,2,3-triazole incorporated quinolone antibiotic conjugates 10–15, 17–19 were synthesized via microwave assisted click chemistry technique. Some of the aryl-substituted conjugates 17–19 show promising antibacterial properties again
    
     
 
       

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Department Related Publications

  • Amany Mohamed Mohamed Elmahmoudy Sanger, "Novel Benzyloxyphenyl Pyrimidine-5-Carbonitrile Derivatives as Potential Apoptotic Antiproliferative Agents", Bentham Science Publishers, 2022 More
  • Tarek Mohamed Salah Rashad, "Exploitation of novel pyrazolo[3,4-d]pyrimidine scaffold tethered to thiazole as potential EGFR/HER2 dual kinase inhibitor to overcome lapatinib resistant breast cancer: Design, synthesis, in silico docking and molecular dynamic simulation", Elsevier, 2025 More
  • Hanan Abdelraziek Abdelfattah Ali Hamied, "Docking,synthesis and biological evaluation of novel pyrazoline derivatives as potential antimicrobial and antitumor agents", India, 2016 More
  • Zakareyah Kamel Abdelsamie, "New synthesis of pyridopyrimidine and pyridotetrahyroquinoline derivatives", Chin. Pharm. J., 1991 More
  • Zakareyah Kamel Abdelsamie, "Synthesis and antibacterial activity of novel benzothiazole, benzimidazole, imidazolidine and imidazo-[2,1-b]-1,3,4-thiadiazole derivatives", Bull. Fac. Pharm. Cairo Univ, 1994 More
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