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SYNTHESIS OF NEW PYRIMIDINE DERIVATIVES AND EVALUATION OF THEIR ANTICANCER AND ANTIMICROBIAL ACTIVITIES
Faculty
Pharmacy
Year:
2016
Type of Publication:
ZU Hosted
Pages:
Authors:
Alaa Nabil Hassan Mustafa Ouf
Staff Zu Site
Abstract In Staff Site
Journal:
Asian journal of pharmaceutical and clinical research Asian J Pharm Clin Res
Volume:
Keywords :
SYNTHESIS , , PYRIMIDINE DERIVATIVES , EVALUATION , THEIR ANTICANCER AND
Abstract:
Objectives: The objective of this work is to synthesize new pyrimidine derivatives starting from ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate. Several oxadiazole, triazole, and thiadiazole moieties were incorporated into the pyrimidine backb
Author Related Publications
Alaa Nabil Hassan Mustafa Ouf, "A vitamin D C/D ring-derived compound with cytotoxicity", web of science, scoupus , pubmed, 2022
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Alaa Nabil Hassan Mustafa Ouf, "Novel Benzyloxyphenyl Pyrimidine-5-Carbonitrile Derivatives as Potential Apoptotic Antiproliferative Agents", web of science, 2022
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Tarek Mohamed Salah Rashad, "New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors", mdpi, 2021
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Nader Elmaghawry Mostafa Abodeah, "Efficient synthesis of N-acylbenzotriazoles using tosyl chloride: en route to suberoylanilide hydroxamic acid (SAHA)", ARKIVOC, 2016
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Tarek Mohamed Salah Rashad, "Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors", Taylor & Francis Group, 2022
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Zakareyah Kamel Abdelsamie, "Synthesis of certain s-triazolo[3,4-b]-1,3,4-thiadiazole derivatives of pharmaceutical interest", Eygpt J. Pharm. Sci, 1987
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Zakareyah Kamel Abdelsamie, "Zurkany. Synthesis and biological activity of new 2-(5-mercapto- 1,3,4-oxadiazol-2- ylmethyl)-4-benzyl-l-(2H)-phthalazinone derivatives", Mans. J. Pharm. Sci, 1990
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