Pentoxifylline abrogates cardiotoxicity induced by the administration of a single high dose or multiple low doses of doxorubicin in rats

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Can J Physiol Pharmacol Can J Physiol Pharmacol Volume:
Keywords : Pentoxifylline abrogates cardiotoxicity induced , , administration , , single    
Abstract:
Doxorubicin (DOX) possesses a broad-spectrum antineoplastic activity; however, its clinical application is impeded by cardiotoxicity. This study aimed to investigate the protective effect of pentoxifylline (PXF), which possesses antioxidant
   
     
 
       

Author Related Publications

  • Shimaa Mostafa Mostafa Elshazly, "The selective 5-LOX inhibitor 11-keto-β-boswellic acid protects against myocardial ischemia reperfusion injury in rats: involvement of redox and inflammatory cascades", Naunyn-Schmiedeberg's Arch Pharmacol, 2012 More
  • Shimaa Mostafa Mostafa Elshazly, "Anticancer activity of salicin and fenofibrate.", zagizag, 2017 More
  • Shimaa Mostafa Mostafa Elshazly, "Ursodeoxycholic acid ameliorates fructose-induced metabolic syndrome in rats.", Springer-Verlag Berlin Heidelberg, 2015 More
  • Shimaa Mostafa Mostafa Elshazly, "Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity.", elsevier, 2015 More
  • Shimaa Mostafa Mostafa Elshazly, "Antifibrotic activity of hesperidin against dimethylnitrosamine induced liver fibrosis in rats.", Springer-Verlag Berlin Heidelberg, 2015 More

Department Related Publications

  • Mona Fouad Mahmoud Abdelaziz, "Beta-caryophyllene protects against diet-induced dyslipidemia and vascular inflammation in rats: Involvement of CB2 and PPAR-γ receptors.", Chem Biol Interact. 2019 Jan 5;297:16-24., 2019 More
  • Hassan Mahmoud Mohamed Elfayomy, "Beta-caryophyllene protects against diet-induced dyslipidemia and vascular inflammation in rats: Involvement of CB2 and PPAR-γ receptors.", Chem Biol Interact. 2019 Jan 5;297:16-24., 2019 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Effect of imidazoline‐1 receptor agonists on renal dysfunction in rats associated with chronic, sequential fructose and ethanol administration", wiley, 2019 More
  • Nasreen Mohammed Ibrahim Moussa, "Effect of imidazoline‐1 receptor agonists on renal dysfunction in rats associated with chronic, sequential fructose and ethanol administration", wiley, 2019 More
  • Shimaa Mostafa Mostafa Elshazly, "Effect of imidazoline‐1 receptor agonists on renal dysfunction in rats associated with chronic, sequential fructose and ethanol administration", wiley, 2019 More
Tweet