Non-carboxylic analogues of aryl-propionic acids: synthesis, anti-inflammatory activity and ulcerogenic potential

Faculty Pharmacy Year: 2007
Type of Publication: ZU Hosted Pages:
Authors:
Journal: European Journal of Medicinal Chemistry Elsevier Volume:
Keywords : Non-carboxylic analogues , aryl-propionic acids: synthesis, anti-inflammatory    
Abstract:
Two series of 1,2,4-triazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles derived from three selected arylpropionic acids namely, ibuprofen, flurbiprofen and naproxen, were synthesized and evaluated for anti-inflammatory activity and ulcer
   
     
 
       

Author Related Publications

  • Kamel Abdelrehem Metwaly Bayomy, "Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study", ELSEVIER, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone‑based rhodanines", Springer Open, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", taylor and francis online, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl t RNA synthetase: design ,synthesis and antibacterial activity against clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone-based rhodanines", Springer, 2017 More

Department Related Publications

  • Osama Ibrahim Abdou Elsabagh, "Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors", Taylor & Francis Group, 2022 More
  • Hend Kather Abdelhakem Elhamalawy, "Synthesis, Anticonvulsant Activity, and SAR Study of Novel 4-Quinazolinone Derivatives", wiley, 2017 More
  • Mahmoud Mohamed Mohamed Sebaee, "Rapid RP-HPLC Method for Simultaneous Estimation of Some Antidiabetics; Metformin, Gliclazide and Glimepiride in Tablets", ejchem.journals.ekb.eg, 2018 More
  • Mansour Alsayed Mansour Abokol, "SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF CERTAIN QUINAZOLINE DERIVATIVES", The Chinese Pharmaceutical Journal Vol., 45, No. 2 pp. 109-114, 1993 More
  • Mansour Alsayed Mansour Abokol, "SYNTHESIS AND PRELIMINARY TESTING OF SOME ANTHRANILIC ACID DERIVATIVES AS ANTIIFLAMMATORY, ANALGESIC AND ANTIPYRETIC AGENTS", Zag. J. Pharm. Sci., Vol. 2 No. 1. Pp 140-149 June, 1993 More
Tweet