Non-carboxylic analogues of aryl-propionic acids: synthesis, anti-inflammatory activity and ulcerogenic potential

Faculty Pharmacy Year: 2007
Type of Publication: ZU Hosted Pages:
Authors:
Journal: European Journal of Medicinal Chemistry Elsevier Volume:
Keywords : Non-carboxylic analogues , aryl-propionic acids: synthesis, anti-inflammatory    
Abstract:
Two series of 1,2,4-triazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles derived from three selected arylpropionic acids namely, ibuprofen, flurbiprofen and naproxen, were synthesized and evaluated for anti-inflammatory activity and ulcer
   
     
 
       

Author Related Publications

  • Kamel Abdelrehem Metwaly Bayomy, "Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study", ELSEVIER, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone‑based rhodanines", Springer Open, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", taylor and francis online, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl t RNA synthetase: design ,synthesis and antibacterial activity against clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone-based rhodanines", Springer, 2017 More

Department Related Publications

  • Mansour Alsayed Mansour Abokol, "SPECTROPHOTOMETRIC DETERMINATION OF KETOPROFEN IN PHARMACEUTICAL PREPARATIONS BY MEANS OF CHARGE TRANSFER COMPLEXES", Talnta. Vol. 40. No. 4 pp. 585-588, 1993 More
  • Mansour Alsayed Mansour Abokol, "REACTION OF 2, 3- DICHLOROMALEIC ANHYDRIDE I: NITROSATIVE REDUCTIVE ELIMINATION; SYNTHESIS OF N-(2,6-DIMETHYLPHENYL)-2-(N-NITROSO-N-SUBSTITUTED)AMINO- SUCCINIMIDES", Chim. Farmaceutico – Anno 135 –pp.429-433 n. 7 Luglio/Agosto, 1996 More
  • Mansour Alsayed Mansour Abokol, "UTILITY OF DICHLOROMALEIMIDE DERIVATIVE AS CHROMOGENIC REAGENT FOR THE SPECTROPHOTOMETRIC DETERMINATION OF CERTAIN FLUOROQUINOLOINES AND RELATED COMPOUNDS", Mansour E.Abou Kull. Zagazig J.Pharm.sci., Dec.(1999) Vol.8 No.2, p13-17, 1999 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Eco-friendly novel deconvoluted synchronous spectrofluorimetric approach for the determination of favipiravir, levodropropizine and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in laboratory prepared mixtures and spiked human plasma", Elsevier, 2023 More
Tweet