GSK-3 heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Am J Physiol Heart Circ Physiol Am J Physiol Heart Circ Physiol Volume:
Keywords : GSK-3 heterozygous knockout , cardioprotective , , knockin mouse    
Abstract:
Glycogen synthase kinase- 3 (GSK-3) plays a central role in both cardiac physiology and pathology. Herein we want to clarify the role of GSK-3 in familial dilated cardiomyopathy. We generated a mouse model carrying a heterozygous kno
   
     
 
       

Author Related Publications

  • Eslam Ahmed Abdelhamid ebrahiem, "β-arrestin-mediated signaling improves the efficacy of therapeutics.", J-STAGE, 2012 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Sildenafil protects against bile duct ligation induced hepatic fibrosis in rats: Potential role for silent information regulator 1 (SIRT1)", ُElsevier, 2017 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Hesperidin protects against stress induced gastric ulcer through regulation of peroxisome proliferator activator receptor gamma in diabetic rats", ELSEVIER, 2018 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Ameliorative effects of clonidine on ethanol induced kidney injury in rats: Potential role for imidazoline-1 receptor.", zagizag, 2018 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Carvedilol protects against hepatic ischemia/reperfusion injury in high-fructose/high-fat diet-fed mice: Role of G protein-coupled receptor kinase 2 and 5", Science direct, 2019 More

Department Related Publications

  • Ibrahim Ali Awaad Awaad AbdelWahab, "7- Comparative study of cardiac safety profiles of loratadine and astemazole in rats", لايوجد, 1900 More
  • Nisreen Elnagy Elwany Mohamed, "Diacerein protects against renal ischemia/reperfusion-induced kidney and lung injuries: involvement of osteopontin and Nrf-2/HO-1 pathway", Zagazig University Medical Journal, 2024 More
  • Rasha Mohamed Sabry, "Mitigation of dexamethasone-induced nephrotoxicity by modulating the activity of adrenergic receptors: Implication of Wnt/β-arrestin2/ β-catenin pathway", Elsevier, 2022 More
  • Shereen Samy Mahmoud Osman, "Protective effect of cerium oxide nanoparticles on cisplatin and oxaliplatin primary toxicities in male albino rats", Springer, 2020 More
  • Shereen Samy Mahmoud Osman, "Protective Effect of Agomelatine against Acetic Acid-Induced Ulcerative Colitis in Male Albino Rats", Association of Cell Biology Romania, 2023 More
Tweet