Pentoxifylline abrogates cardiotoxicity induced by the administration of a single high dose or multiple low doses of doxorubicin in rats

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Can. J. Physiol. Pharmacol. NRC Research Press Volume:
Keywords : Pentoxifylline abrogates cardiotoxicity induced , the administration , , single    
Abstract:
Doxorubicin (DOX) possesses a broad-spectrum antineoplastic activity; however, its clinical application is impeded by cardiotoxicity. This study aimed to investigate the protective effect of pentoxifylline (PXF), which possesses antioxidant
   
     
 
       

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