PARP-1 inhibition alleviates diabetic cardiac complications in experimental animals

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages: 444-454
Authors:
Journal: European journal of pharmacology Elsevier Volume:
Keywords : PARP-1 inhibition alleviates diabetic cardiac complications    
Abstract:
Cardiovascularcomplicationsarethemajorcausesofmortalityamongdiabeticpopulation.Poly(ADP- ribose) polymerase-1enzyme(PARP-1)isactivatedbyoxidativestressleadingtocellulardamage.We investigatedtheimplicationofPARP-1indiabeticcardiaccomplicat
   
     
 
       

Author Related Publications

  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Nitric-Oxide-Mediated Vasodilation of Bioactive Compounds Isolated from Hypericum revolutum in Rat Aorta", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance", FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Interference with TGF beta 1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Rp-HPLC Determination of Quercetin in a Novel D-alpha-Tocopherol Polyethylene Glycol 1000 Succinate Based SNEDDS Formulation: Pharmacokinetics in Rat Plasma", MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Modulation of preeclampsia by the cholinergic anti-inflammatory pathway: Therapeutic perspectives", PERGAMON-ELSEVIER SCIENCE LTD, 2021 More

Department Related Publications

  • Amro Abdelraof Abdelghany Mahmoud, "Antifibrotic activity of hesperidin against dimethylnitrosamineinduced liver fibrosis in rats", Springer, 2014 More
  • Amro Abdelraof Abdelghany Mahmoud, "Hibiscus sabdariffa extract alleviates vascular complications in streptozotocin-induced diabetic rats", Faculty of Pharmacy, Zagazig University, 2016 More
  • Eslam Ahmed Abdelhamid ebrahiem, "GSK-3 heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy", Am J Physiol Heart Circ Physiol, 2016 More
  • Mona Fouad Mahmoud Abdelaziz, "Mexican tea (Dysphania ambrosioides (L.) Mosyakin & Clemants) seeds attenuate tourniquet-induced hind limb ischemia–reperfusion injury by modulating ROS and NLRP3 inflammasome pathways", Elsevier, 2023 More
  • Mona Fouad Mahmoud Abdelaziz, "Euphorbia honey: a comprehensive compile of its traditional use, quality parameters, authenticity, adulteration, and therapeutic merits", Springer Netherlands, 2023 More
Tweet