Modulation of Clonazepam Solubility using Solid Dispersion Technique Improves its Solubility and Bioavailability

Faculty Pharmacy Year: 2012
Type of Publication: ZU Hosted Pages: 446-455
Authors:
Journal: Asian Journal of Research in Chemistry A & V Publications India Volume:
Keywords : Modulation , Clonazepam Solubility using Solid Dispersion    
Abstract:
Abstract The pharmacologic efficacy of benzodiazepines (as clonazepam, CZP) in controlling seizures is directly associated with their plasma concentration. An emergent epileptic situation necessitates rapid drug absorption. parentral adm
   
     
 
       

Author Related Publications

  • Nagia] Ahmed Alameen Elmgrab, "Novel Aqueous solvent based method for protein based nanoparticles.", Association of Biotechnology and pharmacy ®., 2008 More
  • Nagia] Ahmed Alameen Elmgrab, "Oestradiol permeation through human skin and silastic membrane: effects of propylene glycol and supersaturation", Elsevier B.V., 1995 More
  • Nagia] Ahmed Alameen Elmgrab, "Ocular controlled delivery of brimonidine using liposomes as a particulate carrier", faculty of pharmac,y zagazig university, 2001 More
  • Nagia] Ahmed Alameen Elmgrab, "Enhancement of Antibacterial Activity of Tetracycline Hydrochloride By Niosomal Encapsulation", the faculty of pharmacy zagazig university, 2005 More
  • Nagia] Ahmed Alameen Elmgrab, "Buccoadhesive Tablets for Delivery of Tramadol Hcl: Design and In Vitro Analysis", University of Alexanderia faculty of pharmacy, 2006 More

Department Related Publications

  • Marwa Helmy Abedullahh, "Silymarin-loaded Eudragit1 RS100 nanoparticles improved the ability of silymarin to resolve hepatic fibrosis in bile duct ligated rats", Elsevier, 2016 More
  • Amr Selim Ahmed Ali Abu Lila, "Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways", Nature, 2018 More
  • Sherif Emam Abdallah Emam, "Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways", Nature, 2018 More
  • Mahmoud Abdalghany Mahmoud Mahdy, "Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways", Nature, 2018 More
  • Fakhreldeen Soliman Ghazy Shehata, "Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways", Nature, 2018 More
Tweet