Modulation of Clonazepam Solubility using Solid Dispersion Technique Improves its Solubility and Bioavailability

Faculty Pharmacy Year: 2012
Type of Publication: ZU Hosted Pages: 446-455
Authors:
Journal: Asian Journal of Research in Chemistry A & V Publications India Volume:
Keywords : Modulation , Clonazepam Solubility using Solid Dispersion    
Abstract:
Abstract The pharmacologic efficacy of benzodiazepines (as clonazepam, CZP) in controlling seizures is directly associated with their plasma concentration. An emergent epileptic situation necessitates rapid drug absorption. parentral adm
   
     
 
       

Author Related Publications

  • Nagia] Ahmed Alameen Elmgrab, "Novel Aqueous solvent based method for protein based nanoparticles.", Association of Biotechnology and pharmacy ®., 2008 More
  • Nagia] Ahmed Alameen Elmgrab, "Oestradiol permeation through human skin and silastic membrane: effects of propylene glycol and supersaturation", Elsevier B.V., 1995 More
  • Nagia] Ahmed Alameen Elmgrab, "Ocular controlled delivery of brimonidine using liposomes as a particulate carrier", faculty of pharmac,y zagazig university, 2001 More
  • Nagia] Ahmed Alameen Elmgrab, "Enhancement of Antibacterial Activity of Tetracycline Hydrochloride By Niosomal Encapsulation", the faculty of pharmacy zagazig university, 2005 More
  • Nagia] Ahmed Alameen Elmgrab, "Buccoadhesive Tablets for Delivery of Tramadol Hcl: Design and In Vitro Analysis", University of Alexanderia faculty of pharmacy, 2006 More

Department Related Publications

  • Amr Selim Ahmed Ali Abu Lila, "Activation of TLR9 by incorporated pDNA within PEG-coated lipoplex enhances anti-PEG IgM production", nature, 2014 More
  • Nagia] Ahmed Alameen Elmgrab, "Oestradiol permeation through human skin and silastic membrane: effects of propylene glycol and supersaturation", Elsevier B.V., 1995 More
  • Abdullah Mohammed Abdullah Ayub, "Sulpiride microemulsions as antipsychotic nasal drug delivery systems: In-vitro and pharmacodynamic study", Journal of Drug Delivery Science and Technology, 2016 More
  • Hanan Mohamed Mahmoud Mostafa Elnahas, "Optimization and Characterization of Eudragit S 100 Microsponges of Fluconazole", www.ijtrd.com, 2016 More
  • Azza Ali Hassan Solyman, "Optimization and Characterization of Eudragit S 100 Microsponges of Fluconazole", www.ijtrd.com, 2016 More
Tweet