Pioglitazone attenuates cardiac fibrosis and hypertrophy in a rat model of diabetic nephropathy

Faculty Pharmacy Year: 2012
Type of Publication: ZU Hosted Pages: 324-333
Authors:
Rania Ali Mohamed Ali Elrashedy
Journal: Journal of Cardiovascular Pharmacology and Therapeutics SAGE Volume: 3
Keywords : Pioglitazone attenuates cardiac fibrosis , hypertrophy , , , model    
Abstract:
Pioglitazone can ameliorate cardiac remodeling by suppressing the gene expression of TGF-b1 and regulating the MMP-2/TIMP-2 system.
    
     
 
       

Author Related Publications

  • Rania Ali Mohamed Ali Elrashedy, "Cilostazol preconditioning alleviates cyclophosphamide-induced cardiotoxicity in male rats: Mechanistic insights into SIRT1 signaling pathway", Elsevier, 2020 More
  • Rania Ali Mohamed Ali Elrashedy, "Beneficial effects of pioglitazone against cardiovascular injury are enhanced by combination with aliskiren in a rat model of diabetic nephropathy", Willy, 2012 More
  • Rania Ali Mohamed Ali Elrashedy, "Bladder function in mice with inducible smooth muscle-specific deletion of the manganese superoxide dismutase gene", APS, 2015 More
  • Rania Ali Mohamed Ali Elrashedy, "Functional and morphological alterations of the urinary bladder in type 2 diabetic FVBdb/db mice", Elsevier Inc, 2016 More
  • Rania Ali Mohamed Ali Elrashedy, "Potential therapeutic roles of 10-dehydrogingerdione and/or pentoxifylline against calcium deposition in aortic tissues of high dietary cholesterol-fed rabbits.", Springer, 2018 More

Department Related Publications

  • Rania Ali Mohamed Ali Elrashedy, "Bladder function in mice with inducible smooth muscle-specific deletion of the manganese superoxide dismutase gene", APS, 2015 More
  • Mohamed Mahmoud Swedy, "Pattern of fatty acids as modulator for dietary iron overload and its influences on testicular function of experime", Academic Journals, 2013 More
  • Mervat Alsayed Ibrahiem Elsayed Askar, "Vanillin as a new modulator candidate for renal injury induced by cisplatin in experimental rats", ELsevier, 2017 More
  • Sally Kamel Abdelattef, "Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries", Wiley, 2017 More
  • Yasmin Kasem Mahmoud, "Sacubitril/valsartan alleviates sunitinib-induced cardiac fibrosis and oxidative stress via improving TXNIP/TRX system and downregulation of NF-ĸB/Wnt/β-catenin/SOX9 signaling", Elsevier, 2024 More
Tweet